HMGCS2 Antibodies

AND HMGCS2 ELISA kits, HMGCS2 Proteins

Many biological assays use antibodies to detect HMGCS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGCS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGCS2 antibodies...

We validate the specificity of these antibodies to HMGCS2 by testing them on tissues known to express HMGCS2 positively and negatively. Browse below to find the HMGCS2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HMGCS2 Infographic by Boster Bio

All HMGCS2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HMGCS2 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A04371
100ul

Anti-HMGCS2 Antibody (C-term)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A04371-1
80 µl

Anti-HMGCS2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04371-2
100 μg/vial

Anti-HMGCS2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M04371
100 μl/vial

HMGCS2 (NM_005518) Human Over-expression Lysate

Human

$628
Cat # LS003158
100 µg

HMGCS2 Overview

Facts about Hydroxymethylglutaryl-CoA synthase, mitochondrial.

HMGCS2 3D structure. Source: alphafold

Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2)

This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. .

Gene Information

Human
Gene Name:	HMGCS2
Uniprot:	P54868
Entrez:	3158

Family

Belongs to:

thiolase-like superfamily

Alternative Names

3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); EC 2.3.3.10; HMG-CoA synthase; hydroxymethylglutaryl-CoA synthase, mitochondrial; mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase

Molecular Weight

Mass (kDA):
56.635 kDA

Genomic Context


Human

Location:	1p12
Sequence:	1; NC_000001.11 (119747996..119768932, complement)

Tissue Specificity

Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas. Very low expression in heart and skeletal muscle. Not detected in brain. The relative expression of isoform 3 (at mRNA level) is highest in heart (70%) and skeletal muscle (60%).