HMGA1 Antibodies

AND HMGA1 ELISA kits, HMGA1 Proteins

Many biological assays use antibodies to detect HMGA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGA1 antibodies...

We validate the specificity of these antibodies to HMGA1 by testing them on tissues known to express HMGA1 positively and negatively. Browse below to find the HMGA1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HMGA1 Infographic by Boster Bio

All HMGA1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HMGA1 Antibody

Human, Mouse

$405
Cat # A01043
100ul

HMGA1 (NM_145903) Human Recombinant Protein

$1062
Cat # PROTP17096
20 µg

Anti-HMGA1 Antibody (C-term)

Human

Flow Cytometry, IF, WB

$299
Cat # A01043-2
80 µl

Anti-HMGA1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01043
100 μl/vial

HMGA1 (NM_145899) Human Over-expression Lysate

Human

$628
Cat # LS003159
100 µg

HMGA1 Overview

Facts about High mobility group protein HMG-I/HMG-Y.

HMGA1 3D structure. Source: alphafold

High mobility group protein HMG-I/HMG-Y (HMGA1)

HMG-I/Y bind preferentially into the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and at the 3'-end processing of mRNA transcripts.

They're also involved in the transcription regulation of genes comprising, or in close proximity to A+T-rich areas. .

Gene Information

Human
Gene Name:	HMGA1
Uniprot:	P17096
Entrez:	3159

Family

Belongs to:

HMGA family

Alternative Names

high mobility group AT-hook 1; High mobility group AT-hook protein 1; High mobility group protein A1; high mobility group protein HMG-I/HMG-Y; High mobility group protein R; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; HMGA1A; HMG-I(Y); HMGIYMGC12816; HMG-R; MGC4242; MGC4854; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y

Molecular Weight

Mass (kDA):
11.676 kDA

Genomic Context


Human

Location:	6p21.31
Sequence:	6; NC_000006.12 (34236873..34246231)

Subcellular Localizations

Nucleus. Chromosome.

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Carcinoma
Adenocarcinoma
Diabetes Mellitus
Tumor Progression
Mammary Neoplasms
Diabetes Mellitus, Non-insulin-dependent
Pancreatic Neoplasm
Malignant Neoplasm Of Breast

Malignant Neoplasm Of Pancreas
Cell Invasion
Insulin Resistance
Carcinogenesis
Neoplasm Invasiveness
Pancreatic Adenocarcinoma
Leukemia

Interacting Proteins

ORC6
PRMT6

Pathways

Cell Growth
Cell Proliferation
Cell Cycle
Pathogenesis
Rna Interference
Cell Death
Chromatin Remodeling
Dna Repair
Localization
Methylation
Spermatogenesis
Cell Differentiation
Senescence

Cellular Senescence
Translation
Cell Development
Angiogenesis
Secretion
Embryo Development
Cell Division

PTMs

Phosphorylation
Acetylation
Methylation
Sumoylation

Reduction
Phosphorothioation
Cleavage
Deacetylation

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGA1

References

PMID: 2505228 by Eckner R., et al. Cloning of cDNAs coding for human HMG I and HMG Y proteins: both are capable of binding to the octamer sequence motif.

PMID: 2701943 by Johnson K.R., et al. Alternative processing of mRNAs encoding mammalian chromosomal high- mobility-group proteins HMG-I and HMG-Y.