HMGCS1 Antibodies

Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)

This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. .

Gene Information

Human
Gene Name:	HMGCS1
Uniprot:	Q01581
Entrez:	3157

Family

Belongs to:
thiolase-like superfamily

Alternative Names

3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble); EC 2.3.3.10; HMG-CoA synthase; HMGCS; hydroxymethylglutaryl-CoA synthase, cytoplasmic; MGC90332

Molecular Weight

Mass (kDA):
57.294 kDA

Genomic Context

Human
Location:	5p12
Sequence:	5; NC_000005.10 (43287470..43313477, complement)

Subcellular Localizations

Cytoplasm.

Diseases

• Glioma
• Malignant Neoplasms
• Liver Carcinoma
• Schizophrenia
• Leukemia
• Liver Neoplasms
• Inflammation
• Hepatitis, Chronic
• Malignant Neoplasm Of Breast
• Neurodegenerative Disorders
• Liver Damage
• Hypoxia
• Leydig Cell Hyperplasia

• Malignant Neoplasm Of Liver
• Carcinogenesis
• Fibrosis
• Refractory Anemia With Ringed Sideroblasts
• Abnormal Degeneration
• Altitude Sickness
• Neuroblastoma

Pathways

• Transport
• Myelination
• Short-chain Fatty Acid Transport
• Lactation
• Parturition
• Response To Hypoxia
• Keratinocyte Differentiation
• Localization
• Spermatogenesis
• Senescence
• Methylation
• Regeneration
• Neuroprotection

• Fatty Acid Transport
• Tissue Regeneration
• Cell Cycle
• Cell Growth
• Luteinization
• Pathogenesis
• Cholesterol Homeostasis

PTMs

• Deacetylation

• Oxidation

• Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGCS1

Best Uses of the HMGCS1 Marker by Boster Bio

When it comes to determining which antibodies to purchase, Boster Bio has several excellent options. In this article, we'll discuss the Boster Bio Anti-HMGCS1 Marker, a Picogram-sensitive ELISA platform, and its Primers. These three options provide a wide range of capabilities to help you get the most from your research. In addition, we'll go over the benefits of using these products.

Boster Bio Anti-HMGCS1 Marker

The Boster Bio Anti-HMGCS1 Antibody (Center) can be used for various applications in immunohistochemistry and Western blotting. This antibody reacts with Human and Mouse HMGCS1. It is manufactured with high affinity and has been thoroughly validated in ELISA and Immunofluorescence. The anti-HMGCS1 antibody is very specific and can detect high levels of HMGCS1 expression in a variety of tissues.

IHC-optimized polyclonal antibody

If you want to perform studies with Human HMGCS1, the Boster Bio HMGCS1-optimulated polyclonal antibody is a great option. It reacts with both Human and Mouse. The boster bio antibody is produced by immunizing rabbits with synthetic peptide 290-317 amino acids from the Central region of human HMGCS1. You can also buy blocking peptide if you don't want to use this reagent.

The Boster antibody is validated by multiple platforms, using known positive and negative samples. High affinity and specificity are achieved by performing experiments on a panel of 250 tissues. It also benefits from the Boster's unique technology and technical support from its distributor Sanbio. In addition, the Boster antibody is validated by the manufacturer, so you can be assured of its accuracy.

Primers

Flow cytometry is an important tool for the study of gene expression in cells or particles. Boster Bio offers polyclonal and monoclonal primary antibodies with high affinity. These antibodies have been widely cited in the field and continue to be highly relevant. Best Uses of the HMGCS1 marker are discussed below. This article will provide an overview of the use of the HMGCS1 marker in flow cytometry.

Immunoblotting

To use Boster Bio HMGCS1 immunoblotting kits, you must first purchase a primary antibody specific for HMGCS1. This antibody reacts with both Human and Mouse proteins. This antibody is available for a variety of applications, including Western blotting, immunohistochemistry, and ELISA. Alternatively, you can purchase a blocking peptide to use as a negative control.