Histone H2A type 1-C Antibodies

AND Hist1h2ac ELISA kits, Histone H2A type 1-C Proteins

Many biological assays use antibodies to detect Histone H2A type 1-C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A type 1-C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A type 1-C antibodies...

We validate the specificity of these antibodies to Histone H2A type 1-C by testing them on tissues known to express Hist1h2ac positively and negatively. Browse below to find the Hist1h2ac antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hist1h2ac Infographic by Boster Bio

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H2AC6 (NM_003512) Human Recombinant Protein

$813
Cat # PROTQ93077
20 µg

Hist1h2ac Overview

Facts about Histone H2A type 1-C.

Histone H2A type 1-C (Hist1h2ac)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Mouse
Gene Name:	Hist1h2ac
Uniprot:	C0HKE2
Entrez:

Family

Belongs to:

histone H2A family

Alternative Names

dJ221C16.4; H2A/l; H2AFLmember L; histone 1, H2ac; histone cluster 1, H2ac; histone H2A type 1-C; Histone H2A/l; histone H2AC; MGC99519

Molecular Weight

Mass (kDA):
14.135 kDA

Genomic Context


Mouse

Location:
Sequence:	;

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms

Pathways

Regulation Of Cell Cycle
Cell Cycle
Regulation Of Signaling
Rna Interference

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hist1h2ac

References

PMID: 7217105 by Pantazis P., et al. Quantitative determination of histone modification. H2A acetylation and phosphorylation.

PMID: 15525528 by de Napoles M., et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.