Helt Antibodies

AND Helt ELISA kits, Helt Proteins

Many biological assays use antibodies to detect Helt, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Helt in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Helt antibodies...

We validate the specificity of these antibodies to Helt by testing them on tissues known to express Helt positively and negatively. Browse below to find the Helt antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Helt Infographic by Boster Bio

All Helt Products

Product

Figures

Specificity

Applications

Price

HELT (NM_001029887) Human Recombinant Protein

$1249
Cat # PROTA6NFD8
20 µg

HELT (NM_001029887) Human Over-expression Lysate

Human

$628
Cat # LS391723
100 µg

Helt Overview

Facts about Hairy and enhancer of split-related protein HELT.

Hairy and enhancer of split-related protein HELT (Helt)

Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'. Required for the development of GABAergic neurons.

Gene Information

Mouse
Gene Name:	Helt
Uniprot:	Q7TS99
Entrez:	234219

Family

Belongs to:

HEY family

Alternative Names

hairy and enhancer of split-related protein HELT; helt bHLH transcription factor; HES/HEY-like transcription factor; Hey-like transcription factor; Megane bHLH factor; Mgn

Molecular Weight

Mass (kDA):
26.973 kDA

Genomic Context


Mouse

Location:	8 B1.1\|8 26.32 cM
Sequence:	8;

Tissue Specificity

Expressed in heart and testis.

Diseases

Idiopathic Hypereosinophilic Syndrome
Nervousness
Brain Ischemia
Ischemia
Melanoma
Malignant Neoplasm Of Breast
Nervous System Disorder
Brain Neoplasms
Muscular Dystrophy, Facioscapulohumeral
Dystrophy
Malignant Neoplasm Of Lung
Parkinson Disease
Edema

Small Cell Carcinoma Of Lung
Retinoblastoma
Malignant Neoplasm Of Stomach
Malignant Neoplasms
Neoplasms
Eye Diseases, Hereditary
Malignant Neoplasm Of Ovary

Pathways

Neurogenesis
Notch Signaling Pathway
Neuron Development
Axon Guidance
Cell Differentiation
Immune Response
Cell Fate Determination
Neuron Differentiation

Localization
Gabaergic Neuron Differentiation

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Helt

References

PMID: 14764602 by Nakatani T., et al. Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system.

PMID: 15071116 by Miyoshi G., et al. Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis.