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HDAC10 Antibodies
AND HDAC10 ELISA kits, HDAC10 Proteins
Many biological assays use antibodies to detect HDAC10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HDAC10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HDAC10 antibodies...
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HDAC10 Infographic by Boster Bio
All HDAC10 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1261
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1261
1 kit, containing one 96-well plate and all necessary reagents
Human
IF, IHC, WB
$523
Cat # M05215-1
100 µl
Cat # M05215-1
100 µl
Human
Flow Cytometry, IHC, WB
$523
Cat # M05215-2
100 µl
Cat # M05215-2
100 µl
HDAC10 Overview
Facts about Polyamine deacetylase HDAC10.
Polyamine deacetylase HDAC10 (HDAC10)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HDAC10 |
| Uniprot: | Q969S8 |
| Entrez: | 83933 |
Family
| Belongs to: |
|---|
| histone deacetylase family |
Alternative Names
DKFZP761B039; EC 3.5.1.98; HD10; histone deacetylase 10; MGC149722
Molecular Weight
Mass (kDA):
71.445 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q13.33 |
| Sequence: | 22; NC_000022.11 (50245183..50251265, complement) |
Tissue Specificity
Ubiquitous. High expression in liver, spleen, pancreas and kidney.
Subcellular Localizations
Cytoplasm. Nucleus. Excluded from nucleoli.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Lung Neoplasms
- Traditional Serrated Adenoma
- Stomach Neoplasms
- Tumor Angiogenesis
- Malignant Neoplasm Of Lung
- Cell Transformation, Neoplastic
- Adenoma
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
Interacting Proteins
- TRIM54
Pathways
- Localization
- Cell Growth
- Pathogenesis
- Cell Proliferation
- Induction Of Apoptosis
- Cell Cycle
- Histone Acetylation
- Angiogenesis
- Protein Phosphorylation
- Gene Silencing
- Osteoblast Differentiation
- Dna Methylation
- Dna Repair
PTMs
- Acetylation
- Deacetylation
Research Areas
- Breast Cancer
- Cancer
- Checkpoint signaling
- Chromatin Research
- Epigenetics
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC10
bosterbio.com/bosterbio-gene-info-cards/HDAC10
References
PMID: 11861901 by Tong J.J., et al. Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.
PMID: 11726666 by Guardiola A.R., et al. Molecular cloning and characterization of a novel histone deacetylase HDAC10.