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- Table of Contents
Facts about Hydroxycarboxylic acid receptor 3.
This pharmacological effect requires nicotinic acid doses which are much higher than those supplied by a standard diet. .
Human | |
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Gene Name: | HCAR3 |
Uniprot: | P49019 |
Entrez: | 8843 |
Belongs to: |
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G-protein coupled receptor 1 family |
G protein-coupled receptor 109B; GPR109B; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GTP-binding protein; HCA3; HCAR3; HM74; HM74B; HM74Puma-g; Niacin receptor 2; NIACR2; Nicotinic acid receptor 2; PUMAG; putative chemokine receptor
Mass (kDA):
44.478 kDA
Human | |
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Location: | 12q24.31 |
Sequence: | 12; NC_000012.12 (122714756..122716811, complement) |
Expression largely restricted to adipose tissue and spleen.
Cell membrane; Multi-pass membrane protein.
PMID: 7505609 by Nomura H., et al. Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors.
PMID: 12522134 by Wise A., et al. Molecular identification of high and low affinity receptors for nicotinic acid.