Hepcidin Antibodies

Hepcidin (HAMP)

Liver-produced hormone which constitutes the primary circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and reduced flow of iron to plasma.

Controls the major flows of iron to plasma: absorption of dietary iron in the intestine, recycling of iron from macrophages, which phagocytose older erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005). .

Gene Information

Human
Gene Name:	HAMP
Uniprot:	P81172
Entrez:	57817

Family

Belongs to:
hepcidin family

Alternative Names

HAMP; HEPC; hepcidin antimicrobial peptide; Hepcidin; HEPCPutative liver tumor regressor; HFE2B; HFE2Bhepcidin; LEAP1; LEAP-1; LEAP1PLTR; Liver-expressed antimicrobial peptide 1; PLTR

Molecular Weight

Mass (kDA):
9.408 kDA

Genomic Context

Human
Location:	19q13.12
Sequence:	19; NC_000019.10 (35282528..35285143)

Tissue Specificity

Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.

Subcellular Localizations

Secreted.

Diseases

• Iron Overload
• Hemochromatosis
• Hereditary Hemochromatosis
• Anemia
• Juvenile Hemochromatosis
• Inflammation
• Iron Deficiency
• Iron Metabolism Disorders
• Liver Carcinoma
• Liver Cirrhosis
• Diabetes Mellitus
• Beta Thalassemia
• Cardiomyopathies

• Malignant Neoplasms
• Thalassemia
• Hepatitis
• Iron Deficiency Anemia
• Liver Diseases
• Hypoxia
• Sideroblastic Anemia

Pathways

• Chemotaxis
• Transport
• Pathogenesis
• Aerotaxis
• Signal Transmission
• Phototaxis
• Hatching
• Electron Transport
• Proteolysis
• Virulence
• Intestinal Absorption
• Translation
• Biofilm Formation

• Localization
• Response To Interleukin-6
• Taxis
• Secretion
• Cell Adhesion
• Proton Transport
• Reproductive Process

PTMs

• Cleavage
• Phosphorylation

• Nitration
• Dephosphorylation

• Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HAMP

Boster Bio - The Best Uses Of The HAMP Marker

Boster Bio is a great place to start if you're looking for high-affinity prima antibodies. Boster Bio is a well-known manufacturer with a wide variety of products. They also have proprietary trade secrets that make it possible to perform sensitive colorimetric analyses. Read on to learn about Steven Boster and his company's history. This article will provide all the information you need to make a decision about a Boster product. This article will also explain how PicoKine(tm), a proprietary ELISA platform was developed by Boster.

Boster provides high-affinity primary antibodies

Boster Bio is an internationally recognized supplier of high-affinity prima antibodies. The company offers a wide range of products including ELISA kits, lysates and buffers as well as a variety reagents. They also offer high affinity secondary antibodies that are highly specific to certain isotypes.

Flow cytometry is a technique that can be applied to a variety of applications in science. This technique is dependent on primary antibodies. Boster supplies both monoclonal or polyclonal antibody. These high-affinity antibodies have been used in scientific research since over 25 years. They have been consistently referenced. Visit Boster's website for more information about their primary antibodies.

Boster Bio's high affinity polyclonal antibodies have been tested for IHC. This is done through multiple testing techniques, including immunohistochemistry. Boster Bio's antibodies have been shown to be robust and highly specific. They are also tested for WB and ELISA. They can also be reused multiple times. Boster Bio can provide the high-affinity primary antibodies for IHC, ELISA kit, or FC. Boster Bio also offers a quality guarantee that ensures their products work as advertised.

The primary-secondary antibody system is the best way to combine both types of antibodies into one tube. You can run a variety of assays using a single primary antibody. Double-labeling allows for more detailed questions to be asked about the specimen, as well as more solid and contextual information. By using both types, you can test more molecular and cellular functions.

Three methods are used in the production of rAbs. These methods are important for evaluating specificity of antibodies. They can help you determine how well the antibodies interact with your samples. These antibodies can be used to purify the antigen and measure it. Boster Bio's high-affinity prima antibodies are the result of a team that includes experts in the field.

The immune system produces a variety of high-affinity primary antibodies to recognize pathogens. Over the course of ongoing immune responses, the immune system constantly evolves its repertoire, resulting in a high-affinity, high-specific Ab panel. However, it is still unclear what the limits of this repertoire diversity and maturation are. After three booster vaccines with tetanustoxoid, two adult volunteers matured on their own. The third vaccination did no harm to the distribution of somatic mutations or the binding rates constants in the Ab collections. Both fully matured repertoires were genetically diverse and dynamic in both cases.

Boster's products can be used to perform sensitive colorimetric tests

A sensitive colorimetric assay that can detect small amounts of protein is necessary. Boster's HAMP markers were used to develop a sensitive colorimetric test. This biosensor allows for sensitive colorimetric assays. Boster's HAMP markers can be used in many applications, including biotechnology, diagnostics, and clinical research.

History of Steven Boster

For those who have ever wondered about Steve Boster's history, you've come to the right place. His public records include his current address, past addresses, mobile numbers, email addresses, and known family members. You can filter this information using Steve Bosters age and current state. You can also see if Steve Boster is married. What's the most interesting part of Steve Boster’s story?

After a long struggle with COVID-19 Steve Boster died in Madison Wisconsin on June 26, 2022. He was the only child of Evelyn Meier Boster and James Meier Boster. He was a soldier in the U.S. Army. Steve is survived not only by his wife but also his two daughters, Crystal Boster and Natosha Pueck. He also had six grandchildren. His siblings include his brother Jack Boster and Sandra Blanton. His niece Kimberly Peck as well as his nephew Cory Boster live in Herrin, IL.