Histone H2A.Z Antibodies

AND H2AZ1 ELISA kits, Histone H2A.Z Proteins

Many biological assays use antibodies to detect Histone H2A.Z, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A.Z in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A.Z antibodies...

We validate the specificity of these antibodies to Histone H2A.Z by testing them on tissues known to express H2AZ1 positively and negatively. Browse below to find the H2AZ1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2AZ1 Infographic by Boster Bio

All H2AZ1 Products

Product

Figures

Specificity

Applications

Price

Human H2AFZ Recombinant Protein

SDS-PAGE, Denatured

$265
Cat # PROTP0C0S5-1
Starting from 10ug

H2A.Z (H2AFZ) (NM_002106) Human Over-expression Lysate

Human

$628
Cat # LS003015
100 µg

H2AZ1 Overview

Facts about Histone H2A.Z.

H2AZ1 3D structure. Source: alphafold

Histone H2A.Z (H2AZ1)

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA access to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also known as histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	H2AZ1
Uniprot:	P0C0S5
Entrez:	3015

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A.Z

Molecular Weight

Mass (kDA):
13.553 kDA

Genomic Context


Human

Location:	4q23
Sequence:	4; NC_000004.12 (99948088..99950275, complement)

Subcellular Localizations

Nucleus. Chromosome.

Interacting Proteins

ACTR6
FH
ZNHIT1

PTMs

Acetylation
Isopeptide bond

Methylation
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2AZ1

References

PMID: 3344202 by Hatch C.L., et al. Sequence of cDNAs for mammalian H2A.Z, an evolutionarily diverged but highly conserved basal histone H2A isoprotein species.

PMID: 1697587 by Hatch C.L., et al. The human histone H2A.Z gene. Sequence and regulation.