Core histone macro-H2A.2 Antibodies

AND H2afy2 ELISA kits, Core histone macro-H2A.2 Proteins

Many biological assays use antibodies to detect Core histone macro-H2A.2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Core histone macro-H2A.2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Core histone macro-H2A.2 antibodies...

We validate the specificity of these antibodies to Core histone macro-H2A.2 by testing them on tissues known to express H2afy2 positively and negatively. Browse below to find the H2afy2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: Acp3

H2afy2 Infographic by Boster Bio

All H2afy2 Products

Product

Figures

Specificity

Applications

Price

H2afy2 Overview

Facts about Core histone macro-H2A.2.

Core histone macro-H2A.2 (H2afy2)

Variant histone H2A which replaces conventional H2A at a subset of nucleosomes where it represses transcription. Nucleosomes compact and wrap DNA into chromatin, restricting DNA access to the cellular machineries which require DNA as a template.

Histones thus play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also known as histone code, and nucleosome remodeling.

Gene Information

Mouse
Gene Name:	H2afy2
Uniprot:	Q8CCK0
Entrez:

Family

Belongs to:

No superfamily

Alternative Names

core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family, member Y2; Histone macroH2A2; macroH2A2; mH2A2

Molecular Weight

Mass (kDA):
40.092 kDA

Genomic Context


Mouse

Location:
Sequence:	;

Diseases

Huntington Disease
Cell Transformation, Neoplastic
Autistic Disorder
Malignant Neoplasms
Teratoma
Neoplasms
Nervousness
Colorectal Neoplasms
Neurodegenerative Disorders

Nerve Degeneration
Microsatellite Instability
Aneuploidy

Pathways

Cell Cycle
Aging
Neurogenesis
Interphase
Localization
Spindle Assembly

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2afy2

References

PMID: 11331621 by Chadwick B.P., et al. Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant.

PMID: 11262398 by Costanzi C., et al. MACROH2A2, a new member of the MACROH2A core histone family.