Beta-galactosidase Antibodies

Beta-galactosidase (GLB1)

Isoform 1: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. .

Gene Information

Human
Gene Name:	GLB1
Uniprot:	P16278
Entrez:	2720

Family

Belongs to:
glycosyl hydrolase 35 family

Alternative Names

Acid beta-galactosidase; beta-galactosidase; betaGalactosidase1; beta-Galactosidase-1; EBP; EC 3.2.1.23; elastin receptor 1 (67kD); Elastin receptor 1; elastin receptor 1, 67kDa; ELNR1; galactosidase, beta 1; GLB1; Lactase; MPS4B

Molecular Weight

Mass (kDA):
76.075 kDA

Genomic Context

Human
Location:	3p22.3
Sequence:	3; NC_000003.12 (32996608..33097230, complement)

Tissue Specificity

Detected in placenta (at protein level) (PubMed:8383699). Detected in fibroblasts and testis (PubMed:2511208).

Subcellular Localizations

[Isoform 1]: Lysosome.; [Isoform 2]: Cytoplasm, perinuclear region. Localized to the perinuclear area of the cytoplasm but not to lysosomes.

Diseases

• Gangliosidosis Gm1
• Gangliosidoses
• Lysosomal Storage Diseases
• Mucopolysaccharidosis Type Ivb
• Mucopolysaccharidosis Iv
• Beta-galactosidase Deficiency
• Storage Disease
• Nervousness
• Hypoxia
• Neoplasms
• Galactosialidosis
• Neurodegenerative Disorders
• Dysostoses

• Metabolic Bone Disorder
• Pfaundler-hurler Syndrome
• Malignant Neoplasms
• Gangliosidosis, Generalized Gm1, Type 1 (disorder)
• Carcinoma
• Celiac Disease
• Diabetes Mellitus

Pathways

• Senescence
• Aging
• Cellular Senescence
• Localization
• Cell Cycle
• Cell Proliferation
• Cell Cycle Arrest
• Germination
• Transport
• Gene Silencing
• Embryo Development
• Replicative Senescence
• Reverse Transcription

• Intracellular Transport
• Rna Interference
• Secretion
• Immune Response
• Transpiration
• Seed Development
• Translation

PTMs

• Nitration
• Phosphorylation

• Glycosylation
• Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLB1

Best Uses Of The GLB1 Marker

If you're a cancer researcher looking for a novel antibody, there are a few things you should know about the GLB1 marker. First, let's review its uses. The GLB1 marker is a protein found in blood cells that helps to identify cancers. In addition to being a useful tool for cancer researchers, GLB1 can also be used to study IL-1b.

IL-1b

The boster bio.GLB1 marker was designed to detect the GLB1 enzyme in human cells and tissues. GLB1 is an enzyme that catalyzes the deposition of beta-galactosidase, a glycoprotein that binds to beta-galactoside substrates. It is widely used as a reporter marker in gene expression studies.