GCLM Antibodies

AND GCLM ELISA kits, GCLM Proteins

Many biological assays use antibodies to detect GCLM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCLM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCLM antibodies...

We validate the specificity of these antibodies to GCLM by testing them on tissues known to express GCLM positively and negatively. Browse below to find the GCLM antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GCLM Infographic by Boster Bio

All GCLM Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GCSm- gamma GCLM Antibody

Human, Monkey, Mouse, Rat

$399
Cat # A02948
100μl

Anti-GCLM Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02948
100 μl

Anti-GCLM Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A02948-1
100ul

GCLM (NM_002061) Human Recombinant Protein

$1062
Cat # PROTP48507
20 µg

Anti-GCLM Rabbit Monoclonal Antibody

+19

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M02948-2
100 μl/vial

GCLM (NM_002061) Human Over-expression Lysate

Human

$628
Cat # LS002730
100 µg

Anti-GCLM Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02948-2
100 µg/vial

GCLM Overview

Facts about Glutamate--cysteine ligase regulatory subunit.

GCLM 3D structure. Source: alphafold

Glutamate--cysteine ligase regulatory subunit (GCLM)

Gene Information

Human
Gene Name:	GCLM
Uniprot:	P48507
Entrez:	2730

Family

Belongs to:

aldo/keto reductase family

Alternative Names

Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; GCS light chain; GLCLRglutamate--cysteine ligase regulatory subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory(30.8kD); Glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase regulatory protein; glutamate-cysteine ligase, modifier subunit; GSC light chain

Molecular Weight

Mass (kDA):
30.727 kDA

Genomic Context


Human

Location:	1p22.1
Sequence:	1; NC_000001.11 (93885199..93910370, complement)

Tissue Specificity

In all tissues examined. Highest levels in skeletal muscle.

Diseases

Liver Carcinoma
Malignant Neoplasms
Schizophrenia
Inflammation
Liver Neoplasms
Neoplasms
Myocardial Infarction
Neurotoxicity Syndromes
Hepatotoxicity
Mental Disorders
Infarction
Lung Diseases
Neurodegenerative Disorders

Malnutrition
Malignant Neoplasm Of Lung
Injury To Liver
Dysequilibrium Syndrome
Atherosclerosis
Lung Diseases, Obstructive
Fibrosis

Pathways

Cell Death
Pathogenesis
Cell Proliferation
Cell Cycle
Conjugation
Localization
Aging
Cell Growth
Response To Oxidative Stress
Inflammatory Response
Sensitization
Prepulse Inhibition
Proestrus

Gastric Emptying
Transport
Cellular Homeostasis
Immune Response
Regulation Of Gene Expression
Cell Cycle Arrest
Innate Immune Response

PTMs

Phosphorylation
Reduction
Cleavage

Oxidation
Glutathionylation
Methylation

Myristoylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCLM

References

PMID: 7826375 by Gipp J.J., et al. Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues.