Alpha-galactosidase A Antibodies

Alpha-galactosidase A (GLA)

Gene Information

Human
Gene Name:	GLA
Uniprot:	P06280
Entrez:	2717

Family

Belongs to:
glycosyl hydrolase 27 family

Alternative Names

agalsidase alfa; Agalsidase alpha; Agalsidase; Alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase 1; Alpha-D-galactoside galactohydrolase; alpha-gal A; alpha-galactosidase A; EC 3.2.1; EC 3.2.1.22; GALA; galactosidase, alpha; GLA; Melibiase

Molecular Weight

Mass (kDA):
48.767 kDA

Genomic Context

Human
Location:	Xq22.1
Sequence:	X; NC_000023.11 (101397803..101407925, complement)

Subcellular Localizations

Lysosome.

Diseases

• Calcinosis
• Fabry Disease
• Vascular Calcification
• Neoplasms
• Malignant Neoplasms
• Osteoporosis
• Osteopenia
• Diabetes Mellitus
• Kidney Diseases
• Kidney Failure, Chronic
• Atherosclerosis
• Inflammation
• Vascular Diseases

• Fracture
• Hypertrophy
• Blood Coagulation Disorders
• Cardiovascular Diseases
• Vitamin K Deficiency
• Bone Diseases
• Metabolic Bone Disorder

Pathways

• Coagulation
• Bone Resorption
• Excretion
• Pathogenesis
• Blood Coagulation
• Secretion
• Cell Growth
• Localization
• Cell Proliferation
• Bone Remodeling
• Aging
• Ossification
• Cell Death

• Menopause
• Bone Mineralization
• Transport
• Cell Differentiation
• Osteoblast Differentiation
• Reverse Transcription
• Cell Adhesion

PTMs

• Carboxylation
• Gamma-carboxylation
• Phosphorylation
• Cleavage
• Decarboxylation
• Oxidation
• Reduction
• Amidation

• Glycosylation
• Methylation
• Dephosphorylation
• Acylation
• Acetylation
• Hydroxylation
• Carbamylation
• Nitration

• Amination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLA

Boster Bio - Best Uses Of The GLA Marker

You may have wondered what the Boster Bio means if you are trying to improve the performance of your website. If you're not aware of the Boster Bio, read on to find out more about him and how the GLA Marker could help your SEO efforts. There are a myriad of ways to use GLA Marker. This article will focus on the best. Then, you can discover other ways to improve the performance of your website.

Boster Bio

The Boster Bio Anti-Human IgM IGHM Rabbit Monoclonal Antibody (catalog number M07469-3) reacts with Human. It can be stored at -20°C for one year or four degrees Celsius for a month. It is possible to purchase blocking peptides of various lengths to block antibodies against a specific immunogen. This antibody can be used in immunofluorescence applications.

Combining GLA with protein vaccines resulted into high levels of neutralizing antibodies as well as F specific cytokines. The effects were also evident in cell culture. In vitro studies have revealed that GLA-SE triggers high neutralizing antibodies against influenza viruses. Additionally it has been found to trigger anti-inflammatory and anti-tumor immune responses in the murine model. However, more research is needed to confirm the safety and effectiveness of these vaccines.

Use the GLA Marker

Using the GLA Marker in Bostr Bio is a speedy and efficient method of testing a variety of GLA-tagged proteins. These antibodies are highly specific and possess a high affinity to GLA, which is a major component of a variety of cell-based assays. The company offers a wide assortment of products that has been tested and verified in a transparent manner for various applications.

In addition, the gla-3 region is enriched in the submembrane portion of the cytoplasm, which suggests that mutations in this gene may be caused by an abnormal production of oocytes. The gla-3 gene-related mutations were amplified through PCR and their DNA sequences were analysed by analyzing both strands. These findings are important for further research into the mice lacking GLA.

Glycerol (GLA) is one of the proteins that has an array of positively charged amino acids surround by hydrophobic residues, has a GLA protein. These residues are docking site that regulates regulators and targets of MAPK. In addition, the GLA-3 protein has two binding sites for MPK-1 one at the position between 66 and 74 (LRKVVRIDR) and the one at the position 99-107 (LRKVVRID).

GLA is linked to a variety of diseases such as Keutel Syndrome, Peripheral Pulmonary Stenosis and Warfarin Pathway. It is also linked with different pathways such as calcium ion binding, protein degradation, and bones' structural component. Boster Bio is available to assist you in testing GLA-deficient mice with this marker.

Tips to optimize your business

To enhance your flow cytometry outcomes, learn how to maximize the quality of your experiments by following these Boster Bio optimization strategies. Flow cytometry is a sophisticated technique that requires you to make several choices in sample preparation. You must first identify the best method of preparation of the sample. Then, you have to decide whether you should utilize a buffer that blocks. The best results will be achieved using the proper concentrations, buffers, and antibodies. Boster Bio also offers troubleshooting solutions to solve common issues.