GCSH Antibodies

AND GCSH ELISA kits, GCSH Proteins

Many biological assays use antibodies to detect GCSH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCSH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCSH antibodies...

We validate the specificity of these antibodies to GCSH by testing them on tissues known to express GCSH positively and negatively. Browse below to find the GCSH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GCSH Infographic by Boster Bio

All GCSH Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GCSH Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A07082
100ul

Human GCSH Recombinant Protein

SDS-PAGE

$250
Cat # PROTP23434
Starting from 20ug

GCSH (NM_004483) Human Over-expression Lysate

Human

$628
Cat # LS002653
100 µg

GCSH Overview

Facts about Glycine cleavage system H protein, mitochondrial.

GCSH 3D structure. Source: alphafold

Glycine cleavage system H protein, mitochondrial (GCSH)

The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).

Gene Information

Human
Gene Name:	GCSH
Uniprot:	P23434
Entrez:	2653

Family

Belongs to:

GcvH family

Alternative Names

GCE; glycine cleavage system H protein, mitochondrial; glycine cleavage system protein H (aminomethyl carrier); lipoic acid-containing protein; mitochondrial glycine cleavage system H-protein; NKH

Molecular Weight

Mass (kDA):
18.885 kDA

Genomic Context


Human

Location:	16q23.2
Sequence:	16; NC_000016.10 (81081945..81096395, complement)

Subcellular Localizations

Mitochondrion.

Diseases

Nonketotic Hyperglycinemia
Hyperglycinemia
Liver Carcinoma
Inborn Errors Of Metabolism
Muscle Hypotonia
Encephalopathies
Drug-induced Liver Injury
Carcinogenesis
Mammary Neoplasms
Hepatotoxicity
Cerebral Palsy
Moderate Mental Retardation

Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Carcinoma
Dyskinetic Syndrome
Malignant Neoplasms
Neoplasms

Interacting Proteins

Pathways

Reverse Transcription
Tube Closure
Drug Resistance
Neural Tube Closure
Translation
Oxidative Phosphorylation
Pathogenesis
Localization

Conjugation
Vacuolar Acidification

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCSH

References

PMID: 1671321 by Koyata H., et al. The glycine cleavage system: structure of a cDNA encoding human H- protein, and partial characterization of its gene in patients with hyperglycinemias.

PMID: 2025283 by Fujiwara K., et al. The primary structure of human H-protein of the glycine cleavage system deduced by cDNA cloning.