GULP1 Antibodies

AND GULP1 ELISA kits, GULP1 Proteins

Many biological assays use antibodies to detect GULP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GULP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GULP1 antibodies...

We validate the specificity of these antibodies to GULP1 by testing them on tissues known to express GULP1 positively and negatively. Browse below to find the GULP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GULP1 Infographic by Boster Bio

All GULP1 Products

Product

Figures

Specificity

Applications

Price

Anti-GULP1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A07590
100ul

CED6 (GULP1) (NM_016315) Human Recombinant Protein

$1249
Cat # PROTQ9UBP9
20 µg

CED6 (GULP1) (NM_016315) Human Over-expression Lysate

Human

$628
Cat # LS051454
100 µg

GULP1 Overview

Facts about PTB domain-containing engulfment adapter protein 1.

GULP1 3D structure. Source: alphafold

PTB domain-containing engulfment adapter protein 1 (GULP1)

May be an adapter protein. Required for efficient phagocytosis of apoptotic cells.

Modulates mobile glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP.

Gene Information

Human
Gene Name:	GULP1
Uniprot:	Q9UBP9
Entrez:	51454

Family

Belongs to:

ced-6 family

Alternative Names

CED6; CED6GULPCED-6; Cell death protein 6 homolog; engulfment adapter protein; FLJ31156; GULP, engulfment adaptor PTB domain containing 1; GULP1; Protein GULP; PTB domain adapter protein CED-6; PTB domain adaptor protein CED-6; PTB domain-containing engulfment adapter protein 1

Molecular Weight

Mass (kDA):
34.49 kDA

Genomic Context


Human

Location:	2q32.1-q32.2
Sequence:	2; NC_000002.12 (188291699..188595926)

Tissue Specificity

Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.

Subcellular Localizations

Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.

Diseases

Inflammation
Autoimmunity
Neoplasms
Alzheimer's Disease
Neoplasm Metastasis
Lung Diseases
Ehlers-danlos Syndrome
Neoplasm Invasiveness
Dissection Of Aorta
Degenerative Polyarthritis
Loeys-dietz Syndrome
Lung Diseases, Obstructive
Chronic Obstructive Airway Disease

Multiple Myeloma
Tumor Angiogenesis
Malignant Neoplasms
Chromosome Breakage
Chimera Disorder
Ovarian Neoplasm
Rheumatoid Arthritis

Pathways

Phagocytosis
Pathogenesis
Cellular Homeostasis
Endocytosis
Ovarian Follicle Development
Clathrin-mediated Endocytosis
Transport
Cellular Senescence
Localization
Senescence
Muscle Hypertrophy

Cell Motility
Lipid Homeostasis
Cell Growth
Angiogenesis
Lipid Transport

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GULP1

References

PMID: 10574771 by Liu Q.A., et al. Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6.

PMID: 10574763 by Smits E., et al. The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells.