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- Table of Contents
Facts about DNA repair protein REV1.
May assist in the initial step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by chemical and physical agents.
Human | |
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Gene Name: | REV1 |
Uniprot: | Q9UBZ9 |
Entrez: | 51455 |
Belongs to: |
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DNA polymerase type-Y family |
DNA repair protein REV1
Mass (kDA):
138.248 kDA
Human | |
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Location: | 2q11.2 |
Sequence: | 2; NC_000002.12 (99400477..99490123, complement) |
Ubiquitous.
Nucleus.
PMID: 10536157 by Lin W., et al. The human REV1 gene codes for a DNA template-dependent dCMP transferase.
PMID: 10760286 by Gibbs P.E.M., et al. The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.