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- Table of Contents
Facts about General transcription factor 3C polypeptide 2.
Required for RNA polymerase III-mediated transcription.
Part of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other secure nuclear and cytoplasmic RNAs.May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1. .
Human | |
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Gene Name: | GTF3C2 |
Uniprot: | Q8WUA4 |
Entrez: | 2976 |
Belongs to: |
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No superfamily |
general transcription factor 3C polypeptide 2; general transcription factor IIIC, polypeptide 2, beta 110kDa; KIAA0011general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD); TF3C-beta; TFIIIC 110 kDa subunit; TFIIIC110Transcription factor IIIC 110 kDa subunit; TFIIIC-BETA; Transcription factor IIIC subunit beta
Mass (kDA):
100.68 kDA
Human | |
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Location: | 2p23.3 |
Sequence: | 2; NC_000002.12 (27325849..27357376, complement) |
Nucleus.
PMID: 7729686 by Sinn E., et al. Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors.