GTF2B Antibodies

AND GTF2B ELISA kits, GTF2B Proteins

Many biological assays use antibodies to detect GTF2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTF2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTF2B antibodies...

We validate the specificity of these antibodies to GTF2B by testing them on tissues known to express GTF2B positively and negatively. Browse below to find the GTF2B antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GTF2B Infographic by Boster Bio

All GTF2B Products

Product

Figures

Specificity

Applications

Price

Anti-TFIIB monoclonal GTF2B Antibody

Human

IHC, ICC, WB

$482
Cat # M06893
100ul

Anti-TFIIB GTF2B Monoclonal Antibody

Bovine, Canine, Chicken, Human, Mouse, Rat, Swine

IF, IHC, WB

$380
Cat # M06893-1
100ul

TFIIB (GTF2B) (NM_001514) Human Recombinant Protein

$1249
Cat # PROTQ00403
20 µg

Anti-TF2B Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M06893-2
100 μl/vial

TFIIB (GTF2B) (NM_001514) Human Over-expression Lysate

Human

$628
Cat # LS002959
100 µg

GTF2B Overview

Facts about Transcription initiation factor IIB.

GTF2B 3D structure. Source: alphafold

Transcription initiation factor IIB (GTF2B)

General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA (PubMed:1876184, PubMed:1946368, PubMed:1517211, PubMed:3818643, PubMed:3029109, PubMed:8413225, PubMed:8515820, PubMed:8516311, PubMed:8516312, PubMed:7601352, PubMed:9420329, PubMed:12931194, PubMed:27193682).

Together with the TATA box-bound TBP forms the center initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex (PubMed:8504927, PubMed:8413225, PubMed:8515820, PubMed:8516311, PubMed:8516312). Published from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP through the next transcription cycle (PubMed:7601352).

Gene Information

Human
Gene Name:	GTF2B
Uniprot:	Q00403
Entrez:	2959

Family

Belongs to:

TFIIB family

Alternative Names

general transcription factor IIB; General transcription factor TFIIB; S300-II; TFIIBTF2BRNA polymerase II transcription factor IIB; transcription initiation factor IIB

Molecular Weight

Mass (kDA):
34.833 kDA

Genomic Context


Human

Location:	1p22.2
Sequence:	1; NC_000001.11 (88852633..88891944, complement)

Tissue Specificity

Expressed in the inner cell mass forming the embryoblast (PubMed:24441171). Not detected in cells from the outer thin layer trophoblast (at protein level) (PubMed:24441171).

Subcellular Localizations

Nucleus. Chromosome. Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis (PubMed:24441171). Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle (PubMed:24441171).