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- Table of Contents
Facts about General transcription factor IIE subunit 1.
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH.
Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase..
Human | |
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Gene Name: | GTF2E1 |
Uniprot: | P29083 |
Entrez: | 2960 |
Belongs to: |
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TFIIE alpha subunit family |
FE; General transcription factor IIE 56 kDa subunit; general transcription factor IIE subunit 1; general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD); general transcription factor IIE, polypeptide 1, alpha 56kDa; TF2E1; TFIIE-A; TFIIE-alpha; Transcription initiation factor IIE subunit alpha
Mass (kDA):
49.452 kDA
Human | |
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Location: | 3q13.33 |
Sequence: | 3; NC_000003.12 (120742744..120783069) |
Nucleus.
PMID: 1956398 by Peterson M.G., et al. Structure and functional properties of human general transcription factor IIE.
PMID: 1956403 by Ohkuma Y., et al. Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE.