GPR62 Antibodies

AND GPR62 ELISA kits, GPR62 Proteins

Many biological assays use antibodies to detect GPR62, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR62 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR62 antibodies...

We validate the specificity of these antibodies to GPR62 by testing them on tissues known to express GPR62 positively and negatively. Browse below to find the GPR62 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR62 Infographic by Boster Bio

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Anti-G-protein coupled receptor 62 GPR62 Antibody

3 Q&As

Human

$399
Cat # A15290
100μl

GPR62 Overview

Facts about G-protein coupled receptor 62.

GPR62 3D structure. Source: alphafold

G-protein coupled receptor 62 (GPR62)

Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538).

Has spontaneous activity for beta-arrestin recruiting (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B probably through receptor heteromerization (PubMed:28827538).

Gene Information

Human
Gene Name:	GPR62
Uniprot:	Q9BZJ7
Entrez:	118442

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor 62; GPCR8; GPR62; G-protein coupled receptor GPCR8; G-protein coupled receptor KPG_005; hGPCR8; KPG_005; MGC26943; probable G-protein coupled receptor 62

Molecular Weight

Mass (kDA):
37.614 kDA

Genomic Context


Human

Location:	3p21.2
Sequence:	3; NC_000003.12 (51955381..51957499)

Tissue Specificity

Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Colocalizes with ARRB2 in the endosome (PubMed:28827538).

PTMs

Glycoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR62

References

PMID: 11165367 by Lee D.K., et al. Identification of four novel human G protein-coupled receptors expressed in the brain.

PMID: 28827538 by Oishi A., et al. Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions.