GPR6 Antibodies

AND GPR6 ELISA kits, GPR6 Proteins

Many biological assays use antibodies to detect GPR6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR6 antibodies...

We validate the specificity of these antibodies to GPR6 by testing them on tissues known to express GPR6 positively and negatively. Browse below to find the GPR6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR6 Infographic by Boster Bio

All GPR6 Products

Product

Figures

Specificity

Applications

Price

Anti-G-protein coupled receptor 6 GPR6 Antibody

Human, Mouse

IF, ICC, WB

$405
Cat # A09376
100ul

Anti-G-protein coupled receptor 6 GPR6 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A09376-1
100ul

GPR6 (NM_005284) Human Over-expression Lysate

Human

$628
Cat # LS002830
100 µg

GPR6 Overview

Facts about G-protein coupled receptor 6.

GPR6 3D structure. Source: alphafold

G-protein coupled receptor 6 (GPR6)

Orphan receptor using constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and cubes myelin inhibition in neurons (By similarity).

. .

Gene Information

Human
Gene Name:	GPR6
Uniprot:	P46095
Entrez:	2830

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor 6; GPR6; G-protein coupled receptor 6; Sphingosine 1-phosphate receptor GPR6

Molecular Weight

Mass (kDA):
37.881 kDA

Genomic Context


Human

Location:	6q21
Sequence:	6; NC_000006.12 (109978256..109980720)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.

Diseases

Pertussis
Malformations Of Cortical Development
Stenosis
Nervous System Disorder
Neurotoxicity Syndromes
Atherosclerosis
Pneumonia
Vascular System Injuries
Tumor Angiogenesis
Polymicrogyria
Complex Partial Seizures

Nervousness
Pituitary Diseases
Dental Plaque
Inflammation
Alzheimer's Disease

Pathways

Cell Proliferation
Localization
Smooth Muscle Cell Proliferation
Muscle Cell Proliferation
Cell Development
Neurogenesis
Oocyte Maturation
Reflex
Neuroprotection
Regeneration

Sensitization
Cell Death
Cell Growth
Angiogenesis
Oogenesis

PTMs

Phosphorylation

Ubiquitination

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR6

References

PMID: 7832990 by Heiber M., et al. Isolation of three novel human genes encoding G protein-coupled receptors.

PMID: 8530049 by Song Z.-H., et al. Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors.