NPBWR2 Antibodies

AND NPBWR2 ELISA kits, NPBWR2 Proteins

Many biological assays use antibodies to detect NPBWR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NPBWR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NPBWR2 antibodies...

We validate the specificity of these antibodies to NPBWR2 by testing them on tissues known to express NPBWR2 positively and negatively. Browse below to find the NPBWR2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NPBWR2 Infographic by Boster Bio

All NPBWR2 Products

Product

Figures

Specificity

Applications

Price

Anti-NPBW2 NPBWR2 Antibody

Human

ELISA, WB

$380
Cat # A10246
100ul

NPBWR2 (NM_005286) Human Over-expression Lysate

Human

$628
Cat # LS002832
100 µg

NPBWR2 Overview

Facts about Neuropeptides B/W receptor type 2.

NPBWR2 3D structure. Source: alphafold

Neuropeptides B/W receptor type 2 (NPBWR2)

Interacts specifically with a range of opioid ligands. Receptor for neuropeptides B and W, which might be involved in neuroendocrine system regulation, food intake and the organization of different signals.

Gene Information

Human
Gene Name:	NPBWR2
Uniprot:	P48146
Entrez:	2832

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

GPR8; GPR-8; neuropeptides B/W receptor 2; NPBWR2

Molecular Weight

Mass (kDA):
36.861 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (64103802..64107565, complement)

Tissue Specificity

Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Pain
Anxiety Disorders
Mood Disorders
Schizophrenia
Hyperphagia
Malignant Neoplasm Of Adrenal Cortex
Nervousness
Pertussis

Bipolar Disorder
Dysequilibrium Syndrome

Interacting Proteins

BOLL
KRT31
KRT40
KRTAP10-7
KRTAP10-9

KRTAP5-9
NOTCH2NL
PNMA1
PSMA3

Pathways

Secretion
Energy Homeostasis
Feeding Behavior
Regulation Of Energy Homeostasis
Regulation Of Saliva Secretion
Saliva Secretion
Insulin Secretion
Glucocorticoid Secretion
Drinking Behavior

Aldosterone Secretion
Regulation Of Feeding Behavior
Cortisol Secretion

PTMs

Disulfide bond
Glycoprotein

Lipoprotein
Palmitate

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPBWR2

References

PMID: 7590751 by O'Dowd B.F., et al. The cloning and chromosomal mapping of two novel human opioid- somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.

PMID: 12401809 by Brezillon S., et al. Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.