GPR52 Antibodies

AND GPR52 ELISA kits, GPR52 Proteins

Many biological assays use antibodies to detect GPR52, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR52 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR52 antibodies...

We validate the specificity of these antibodies to GPR52 by testing them on tissues known to express GPR52 positively and negatively. Browse below to find the GPR52 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN4 Next: S1PR2

GPR52 Infographic by Boster Bio

All GPR52 Products

Product

Figures

Specificity

Applications

Price

Anti-G-protein coupled receptor 52 GPR52 Antibody

4 Q&As

Human

$399
Cat # A13015
100μl

Anti-G-protein coupled receptor 52 GPR52 Antibody

Human, Mouse, Rat

$405
Cat # A13015-1
100ul

GPR52 Overview

Facts about G-protein coupled receptor 52.

GPR52 3D structure. Source: alphafold

G-protein coupled receptor 52 (GPR52)

Gs-coupled receptor triggered by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity.

These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level through cAMP-dependent but PKA independent mechanics throught activation of RAB39B which translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).

Gene Information

Human
Gene Name:	GPR52
Uniprot:	Q9Y2T5
Entrez:	9293

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor 52; GPR52; MGC111751; probable G-protein coupled receptor 52

Molecular Weight

Mass (kDA):
41.354 kDA

Genomic Context


Human

Location:	1q25.1
Sequence:	1; NC_000001.11 (174447964..174449545)

Tissue Specificity

Expressed in brain, especially in striatum.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

PTMs

Disulfide bond

Glycoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR52

References

PMID: 9931487 by Sawzdargo M., et al. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.

PMID: 24587241 by Komatsu H., et al. Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.