GPR17 Antibodies

AND GPR17 ELISA kits, GPR17 Proteins

Many biological assays use antibodies to detect GPR17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR17 antibodies...

We validate the specificity of these antibodies to GPR17 by testing them on tissues known to express GPR17 positively and negatively. Browse below to find the GPR17 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR17 Infographic by Boster Bio

All GPR17 Products

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Specificity

Applications

Price

Anti-GPR17 Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A07718
100ul

Anti-GPR17 Mouse Monoclonal Antibody [Clone ID: OTI17C1]

Human, Mouse, Rat

IHC, WB

$523
Cat # M07718
100 µl

GPR17 Overview

Facts about Uracil nucleotide/cysteinyl leukotriene receptor.

GPR17 3D structure. Source: alphafold

Uracil nucleotide/cysteinyl leukotriene receptor (GPR17)

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase.

May mediate brain damage by nucleotides and CysLTs after ischemia. .

Gene Information

Human
Gene Name:	GPR17
Uniprot:	Q13304
Entrez:	2840

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

DKFZp686M18273; G protein-coupled receptor 17; GPR17; G-protein coupled receptor 17; P2Y-like Receptor; R12; UDP/CysLT Receptor; uracil nucleotide/cysteinyl leukotriene receptor

Molecular Weight

Mass (kDA):
40.989 kDA

Genomic Context


Human

Location:	2q14.3
Sequence:	2; NC_000002.12 (127645864..127652639)

Tissue Specificity

Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Brain Injuries
Ischemia
Nervousness
Inflammation
Brain Ischemia
Neoplasms
Multiple Sclerosis
Sclerosis
Tissue Damage
Infarction
Neurodegenerative Disorders
Cerebrovascular Accident
Asthma

Nerve Degeneration
Demyelinating Diseases
Spinal Cord Injuries
Glioma
Trauma, Nervous System
Brain Hypoxia
Malignant Neoplasms

Pathways

Oligodendrocyte Differentiation
Cell Death
Localization
Myelination
Cell Maturation
Cell Cycle
Cell Proliferation
Mitosis
Anaphylaxis
Neurogenesis
Regulation Of Gene Expression
Mucus Secretion
Glucose Homeostasis

Neuroprotection
Swimming
Sensitization
Chemotaxis
Cell Differentiation
Store-operated Calcium Entry
Secretion

PTMs

Phosphorylation

Research Areas

GPCR
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR17

References

PMID: 8558062 by Raport C.J., et al. New members of the chemokine receptor gene family.

PMID: 9523551 by Blaesius R.H., et al. A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21.