Glypican-4 Antibodies

AND GPC4 ELISA kits, Glypican-4 Proteins

Many biological assays use antibodies to detect Glypican-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Glypican-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Glypican-4 antibodies...

We validate the specificity of these antibodies to Glypican-4 by testing them on tissues known to express GPC4 positively and negatively. Browse below to find the GPC4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN2 Next: FGD1

GPC4 Infographic by Boster Bio

All GPC4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human Glypican 4 Recombinant Protein

SDS-PAGE

$265
Cat # PROTO75487
Starting from 10ug

GPC4 Overview

Facts about Glypican-4.

GPC4 3D structure. Source: alphafold

Glypican-4 (GPC4)

Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity).

. .

Gene Information

Human
Gene Name:	GPC4
Uniprot:	O75487
Entrez:	2239

Family

Belongs to:

glypican family

Alternative Names

Glypican 4; glypican proteoglycan 4; glypican-4; GPC4; K-glypican; K-glypicandJ900E8.1 (glypican 4)

Molecular Weight

Mass (kDA):
62.412 kDA

Genomic Context


Human

Location:	Xq26.2
Sequence:	X; NC_000023.11 (133300103..133415489, complement)

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Secreted glypican-4]: Secreted, extracellular space.

Diseases

Simpson-golabi-behmel Syndrome, Type 1
Neoplasms
Gigantism
Carcinoma
Cartilaginous Exostosis
Malignant Neoplasms
Nervousness
Genetic Diseases, X-linked
Beckwith-wiedemann Syndrome
Chromosomal Translocation
Limb Deformities, Congenital

Intraepithelial Neoplasia
Cardiac Arrhythmia
Neurodegenerative Disorders
Uterine Cervical Neoplasm
Bone Neoplasms
Hydrocephalus

Pathways

Cell Division
Gastrulation
Cell Growth
Neural Tube Closure
Convergent Extension
Localization
Tube Closure
Stem Cell Differentiation
Brain Development
Neurogenesis
Ossification
Progression Of Neural Tube Closure
Cell Fate Specification

Translation
Cell Cycle
Cell Differentiation
Bone Morphogenesis
Initiation Of Neural Tube Closure
Regulation Of Cell Cycle
Endochondral Ossification

PTMs

Sulphation

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPC4

References

PMID: 9787072 by Veugelers M., et al. GPC4, the gene for human K-glypican, flanks GPC3 on Xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome.

PMID: 10814714 by Veugelers M., et al. Mutational analysis of the GPC3/GPC4 glypican gene cluster on Xq26 in patients with Simpson-Golabi-Behmel syndrome: identification of loss- of-function mutations in the GPC3 gene.