RAB6-interacting golgin Antibodies

RAB6-interacting golgin (GORAB)

Gene Information

Human
Gene Name:	GORAB
Uniprot:	Q5T7V8
Entrez:	92344

Family

Belongs to:
GORAB family

Alternative Names

FLJ11752; golgin, RAB6-interacting; GONTKL-binding protein 1; hNTKL-BP1; MGC51263; MGC70512; N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKLBP1SCY1-like 1-binding protein 1; RAB6-interacting golgin; SCY1-like 1 binding protein 1; SCYL1-BP1; SCYL1BP1SCYL1-binding protein 1

Molecular Weight

Mass (kDA):
44.993 kDA

Genomic Context

Human
Location:	1q24.2
Sequence:	1; NC_000001.11 (170532134..170553834)

Subcellular Localizations

Cytoplasm. Golgi apparatus.

Diseases

• Cutis Laxa
• Prognathism
• Osteopenia
• Dwarfism
• Severe Mental Retardation
• Skin Diseases, Genetic
• Bone Diseases

• Geroderma Osteodysplastica

Interacting Proteins

• MDM2

Pathways

• Glycosylation
• Membrane Fusion
• Pathogenesis
• Localization

PTMs

• Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GORAB

Best Uses of the GORAB Marker

Boster Bio Company, which was founded in 1993, specializes in antibody production and ELISA related molecular biology products. It also provides scientists with technical support and free technical resources. Here are some tips and tricks for those who want to integrate the GORAB Marker into research.

Benefits of using GORAB Marker

Both swaging as well as embedding require a specialized device. Both require specialized equipment. However, the upfront cost of embedding a marker band is higher. It is possible to fail to embed a markerband, which can lead to a higher cost. Here are some of the advantages of using a GORAB Marker. These benefits may outweigh any disadvantages.

Sources of primary antibodies

Secondary antibodies are used for the detection of the target antigen. Secondary antibodies must match primary antibodies and the class or the subclass of the target antigen. For example, primary antibodies from the same species are monoclonal. Monoclonal antibodies, on the other side, are more complex, and can be divided into several classes and subtypes. This article will explain the differences between the subtypes, as well as how to select the right secondary antibodies for your research.

Secondary antibodies can be made in many species. Common hosts are goat, chicken, donkey and rabbit cells. These samples won't have any endogenous immunoglobulins, but they will have immunoglobulins ranging from 50 to 25kDa. In general, the secondary antibody source must be rabbit-derived. The GORAB marker is used for the distinction between these two types.

COPI acts as a mediator of protein transport in the secretory route. It recruits Arf GTPases and undergoes assembly to form coated transport intermediates that traffic numerous proteins and Golgi resident enzymes. Gorab is mutated by the skin disorder gerodermia. GORAB also forms stable domains inside the trans-Golgi. It is involved with the recruitment of COPI by interfacing with Scyl1. Pathogenic GORAB variants can disrupt Scyl1 assembly and binding.

Secondary antibodies are generated by immunizing a host animal with antigens of a particular species. For example, a goat immunized with mouse IgG will produce anti-mouse antibodies that bind to all classes and fragments of the mouse IgG, while a donkey will generate antibodies that are specific to mouse IgG1.

There are many antibodies that recognize the same epitope in different host tissues. These secondary antibodies recognize the exact same epitope on different target-antigens and are useful for many applications. They can be used in multiplexing, multi-labeling, and validation of target antigen detection. They are available from a variety. This article can help you to find primary antibodies if you are looking for them.

Citations of product

Boster Bio is a manufacturer and distributor of high-quality primary antibody for diagnostic and research purposes. Boster Bio is a well-established company with a long history in this field. The company was founded in 1990 by Steven Boster, who was known for his innovations and the nickname "he who converted science in the lavatory". Steven's expertise in the development of primary antibodies allowed Boster to build the largest catalog antibody company in China by the late 1990s. Boster Bio is a leader within the field of primary antibodies as well as ELISA kits and has been dubbed "the most advanced antibody company" in the world.

Implementation of Bioz Ciation Counters

Bosteer Bio's new implementation of Bioz Citation Counters is making it easier for researchers to be more productive. Elsevier offers the service in more 100 research journals. Boster Bio, an internet citation management tool, has Bioz Citation Counters. Researchers can also view the number of citations received by their papers in a specified time frame using this feature.