GNPTG Antibodies

AND GNPTG ELISA kits, GNPTG Proteins

Many biological assays use antibodies to detect GNPTG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNPTG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNPTG antibodies...

We validate the specificity of these antibodies to GNPTG by testing them on tissues known to express GNPTG positively and negatively. Browse below to find the GNPTG antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GNPTG Infographic by Boster Bio

All GNPTG Products

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Specificity

Applications

Price

GNPTG (NM_032520) Human Recombinant Protein

$813
Cat # PROTQ9UJJ9
20 µg

GNPTG (NM_032520) Human Over-expression Lysate

Human

$628
Cat # LS084572
100 µg

GNPTG Overview

Facts about N-acetylglucosamine-1-phosphotransferase subunit gamma.

GNPTG 3D structure. Source: alphafold

N-acetylglucosamine-1-phosphotransferase subunit gamma (GNPTG)

Non-catalytic subunit of the N-acetylglucosamine-1- phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB).

Enhances the speed of N-acetylglucosamine- 1-phosphate move to the oligosaccharides of acid hydrolase acceptors. .

Gene Information

Human
Gene Name:	GNPTG
Uniprot:	Q9UJJ9
Entrez:	84572

Family

Belongs to:

No superfamily

Alternative Names

C16orf27; c316G12.3; CAB56184; GlcNAc-1-phosphotransferase subunit gamma; GNPTAGchromosome 16 open reading frame 27; LP2537; N-acetylglucosamine-1-phosphate transferase, gamma subunit; N-acetylglucosamine-1-phosphotransferase subunit gamma; N-acetylglucosamine-1-phosphotransferase, gamma subunit; RJD9; UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma

Molecular Weight

Mass (kDA):
33.974 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (1351931..1364113)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Secreted. Golgi apparatus.

Diseases

Mucolipidoses
Pseudo-hurler Polydystrophy
Type Ii Mucolipidosis
Stuttering
Speech Disorders
Lysosomal Storage Diseases
Neuropathology Disease
Pfaundler-hurler Syndrome
Specific Language Impairment
Mutation, Out-of-frame
Retinal Degeneration
Endometrial Polyp

Dyslexia
Carcinoma
Arthralgia
Dysplasia
Endometritis
Flushing
Puerperal Disorders

Pathways

Transport
Glycosylation
Cell Adhesion
Secretion Of Lysosomal Enzymes
Secretory Pathway
Translational Termination
Constitutive Secretory Pathway
Localization
Operant Conditioning

Macrophage Differentiation
Cell Cycle
Excretion
Secretion

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNPTG

References

PMID: 10712439 by Raas-Rothschild A., et al. Molecular basis of variant pseudo-Hurler polydystrophy (mucolipidosis IIIC).

PMID: 15060128 by Raas-Rothschild A., et al. Genomic organisation of the UDP-N-acetylglucosamine-1- phosphotransferase gamma subunit (GNPTAG) and its mutations in mucolipidosis III.