Acyl-CoA (8-3)-desaturase Antibodies

AND FADS1 ELISA kits, Acyl-CoA (8-3)-desaturase Proteins

Many biological assays use antibodies to detect Acyl-CoA (8-3)-desaturase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acyl-CoA (8-3)-desaturase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acyl-CoA (8-3)-desaturase antibodies...

We validate the specificity of these antibodies to Acyl-CoA (8-3)-desaturase by testing them on tissues known to express FADS1 positively and negatively. Browse below to find the FADS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FADS1 Infographic by Boster Bio

All FADS1 Products

Product

Figures

Specificity

Applications

Price

Anti-FADS1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02535
100 μl/vial

FADS1 (NM_013402) Human Over-expression Lysate

Human

$628
Cat # LS003992
100 µg

Anti-FADS1 Antibody Picoband™

Human

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A02535-1
100 μg/vial

FADS1 Overview

Facts about Acyl-CoA (8-3)-desaturase.

FADS1 3D structure. Source: alphafold

Acyl-CoA (8-3)-desaturase (FADS1)

Isoform 2 doesn't exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3).

Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively. .

Gene Information

Human
Gene Name:	FADS1
Uniprot:	O60427
Entrez:	3992

Family

Belongs to:

fatty acid desaturase type 1 family

Alternative Names

D5DFLJ90273; Delta(5) desaturase; Delta(5) fatty acid desaturase; Delta-5 desaturase; delta-5 fatty acid desaturase; EC 1.14.19; EC 1.14.19.-; FADS6; FADSD5LLCDL1; fatty acid desaturase 1; FLJ38956; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1; TU12

Molecular Weight

Mass (kDA):
51.964 kDA

Genomic Context


Human

Location:	11q12.2
Sequence:	11; NC_000011.10 (61799627..61817003, complement)

Tissue Specificity

Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.

Subcellular Localizations

[Isoform 1]: Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion.; [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.