GNAT1 Antibodies

AND GNAT1 ELISA kits, GNAT1 Proteins

Many biological assays use antibodies to detect GNAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNAT1 antibodies...

We validate the specificity of these antibodies to GNAT1 by testing them on tissues known to express GNAT1 positively and negatively. Browse below to find the GNAT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GNAT1 Infographic by Boster Bio

All GNAT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-GNAT1/Transducin Alpha Antibody

1 Q&As

Human, Mouse

$360
Cat # A04598
100 µl

Anti-G alpha t1 Antibody

12 Q&As

Human, Mouse, Rat

$399
Cat # A04598-1
100μl

Anti-G Alpha t1 (M104) GNAT1 Antibody

Human, Mouse, Rat

$405
Cat # A04598t1
100ul

GNAT1 Overview

Facts about Guanine nucleotide-binding protein G(t) subunit alpha-1.

GNAT1 3D structure. Source: alphafold

Guanine nucleotide-binding protein G(t) subunit alpha-1 (GNAT1)

Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception from the retina (PubMed:22190596).

Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an energetic, GTP-bound state and an inactive, GDP-bound state.

Gene Information

Human
Gene Name:	GNAT1
Uniprot:	P11488
Entrez:	2779

Family

Belongs to:

G-alpha family

Alternative Names

CSNBAD3; GBT1; GNATR; guanine nucleotide binding protein (G protein), alpha transducing activitypolypeptide 1; guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; rod-type transducin alpha subunit; Transducin alpha-1 chain; transducin, rod-specific

Molecular Weight

Mass (kDA):
40.041 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (50191610..50197696)

Tissue Specificity

Rod photoreceptor cells (PubMed:1614872). Predominantly expressed in the retina followed by the ciliary body, iris and retinal pigment epithelium (PubMed:22190596).

Subcellular Localizations

Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein. Photoreceptor inner segment. Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.