This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Guanine nucleotide-binding protein G(t) subunit alpha-2.
.
Human | |
---|---|
Gene Name: | GNAT2 |
Uniprot: | P19087 |
Entrez: | 2780 |
Belongs to: |
---|
G-alpha family |
Guanine nucleotide-binding protein G(t) subunit alpha-2
Mass (kDA):
40.176 kDA
Human | |
---|---|
Location: | 1p13.3 |
Sequence: | 1; NC_000001.11 (109603091..109619538, complement) |
Retinal rod outer segment.
Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.
PMID: 2534964 by Lerea C.L., et al. Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina.
PMID: 1936270 by Kubo M., et al. Molecular cloning and sequence analysis of cDNA and genomic DNA for the human cone transducin alpha subunit.