Zinc finger protein GLIS3 Antibodies

AND GLIS3 ELISA kits, Zinc finger protein GLIS3 Proteins

Many biological assays use antibodies to detect Zinc finger protein GLIS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein GLIS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein GLIS3 antibodies...

We validate the specificity of these antibodies to Zinc finger protein GLIS3 by testing them on tissues known to express GLIS3 positively and negatively. Browse below to find the GLIS3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GLIS3 Infographic by Boster Bio

All GLIS3 Products

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Product

Figures

Specificity

Applications

Price

Anti-GLIS3 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A03710-3
100 μg/vial

GLIS3 (NM_001042413) Human Over-expression Lysate

Human

$960
Cat # LS169792
100 µg

GLIS3 Overview

Facts about Zinc finger protein GLIS3.

GLIS3 3D structure. Source: alphafold

Zinc finger protein GLIS3 (GLIS3)

Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).

. .

Gene Information

Human
Gene Name:	GLIS3
Uniprot:	Q8NEA6
Entrez:	169792

Family

Belongs to:

GLI C2H2-type zinc-finger protein family

Alternative Names

FLJ38999; FLJ90578; GLIS family zinc finger 3; GLI-similar 3; OK/KNS-cl.4; zinc finger protein 515; zinc finger protein GLIS3

Molecular Weight

Mass (kDA):
83.636 kDA

Genomic Context


Human

Location:	9p24.2
Sequence:	9; NC_000009.12 (3824127..4310694, complement)

Tissue Specificity

In the adult, expressed at high levels in the kidney and at lower levels in the brain, skeletal muscle, pancreas, liver, lung, thymus and ovary.

Subcellular Localizations

Nucleus.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Hypothyroidism
Cystic Kidney Diseases
Congenital Hypothyroidism
Kidney Diseases
Fibrosis
Neoplasms
Hyperglycemia
Malignant Neoplasms
Glaucoma
Diabetes Mellitus, Insulin-dependent

Polycystic Kidney Diseases
Hepatic Fibrosis
Congenital Anomaly Of Face
Insulin Resistance
Developmental Delay (disorder)
Insulin Sensitivity

Pathways

Glucose Homeostasis
Cell Proliferation
Insulin Secretion
Localization
Secretion
Cell Development
Pathogenesis
Transdifferentiation
Regeneration

Osteoblast Differentiation
Cell Differentiation
Response To Metformin

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLIS3

References

PMID: 16715098 by Senee V., et al. Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

PMID: 14500813 by Kim Y.-S., et al. GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions.