GLDC Antibodies

Glycine dehydrogenase (decarboxylating), mitochondrial (GLDC)

The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).

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Gene Information

Human
Gene Name:	GLDC
Uniprot:	P23378
Entrez:	2731

Family

Belongs to:
GcvP family

Alternative Names

EC 1.4.4.2; GCE; GCSPMGC138198; Glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase P-protein; Glycine decarboxylase; glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavagesystem protein P); glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; MGC138200; NKH

Molecular Weight

Mass (kDA):
112.73 kDA

Genomic Context

Human
Location:	9p24.1
Sequence:	9; NC_000009.12 (6532467..6645729, complement)

Subcellular Localizations

Mitochondrion.

Diseases

• Nonketotic Hyperglycinemia
• Hyperglycinemia
• Encephalopathies
• Muscle Hypotonia
• Neoplasms
• Apnea
• Brain Diseases
• Disorder Of Glycine Metabolism
• Inborn Errors Of Metabolism
• Neonatal Hypotonia
• Moderate Mental Retardation

• Personality Disorders
• Learning Disabilities
• Hypoxia
• Behavioral Tic
• Dyskinetic Syndrome
• Malignant Neoplasms

Pathways

• Tube Closure
• Neural Tube Closure
• Cell Proliferation
• Translation
• Pathogenesis
• Glycolysis

• Excretion

PTMs

• Cleavage

Research Areas

• Core ESC-Like Genes
• Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLDC

Boster Bio - The Best Uses Of The GLDC Marker

High-affinity primary antibodies are an essential part of many research protocols. Moreover, they can be used to optimize a variety of biological experiments. Here are some useful tips and guides for optimizing your experiments. These guides can also answer your queries about Boster Bio and its GLDC Marker. Let's begin. Listed below are Boster Bio's key advantages and features.

High-affinity primary antibodies

The GLDC marker is an antigen present on the surface of cells that serves as a reference to identify various organelles. It has two levels of purity: low and high. A high-affinity primary antibody detects the antigen at the lowest concentration. It is the most commonly used marker for detecting GLDC. High-affinity primary antibodies can also be used to detect multiple cellular proteins.

GLDC Marker

The GLDC marker has several potential uses in cancer research. This gene is a regulator of glycolysis and does not promote glycine uptake. Interestingly, this gene is upregulated in several human cancers, including NSCLC. It may be useful in the detection of various cancers, including ovarian and pancreatic cancer. The following article will discuss some of the possible uses of the GLDC marker in cancer research.

The GLDC gene is known by several names: MSX1, ERRFI1, TNFRSF12A, PTPRF, IGFBP2, and TWIST. In this study, the GLDC marker was used to identify cancer cells in patients with metastatic disease and compared with patients with non-metastatic disease. Tumorproben has shown promising results in these patients.

Optimization

The GLDC protein is a key element in the regulation of cell cycle. It is involved in cellular processes including cell division and hormone secretion. Several genetic variations have been found to have alterations in the GLDC marker. In this study, the GLDC marker was used to detect NKH mutations. This marker is important in the detection of cancer, as it may be involved in the progression of leukemia and other diseases.

The MMS was applied to 18 homozygous GLDC mutations and 24 clinical cases. The MMS scores for each patient mutation were then added to the COS. These results were further validated by using the Exome Aggregation Consortium (ExAC) database, which contains genomic data from healthy people. By doing this, a control group of healthy individuals was included to check for sensitivity and specificity of the marker.

Steven Boster's history

To learn more about Steven Boster's history, explore the company's public records. These records show details such as Boster's current and past addresses, contact information, and even email addresses. There are also records of known family members. Search for Steve Boster by state or age to narrow down your results. He was a self-proclaimed "science geek" who was a big fan of southern gospel. Here are some interesting facts about Steve Boster.

Steve Boster was born in Joliet, IL. He worked as a manager in retail sales for many years. He was also a member of Concordia Hall in Staunton, VA. In addition to his family, he is survived by two Daughters, Natosha Peck and Crystal Boster, 6 Grandchildren, 4 Brothers (Jack Boster and Sandra Blanton), and several nieces and nephews.