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- Table of Contents
Facts about Nucleoporin GLE1.
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Human | |
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Gene Name: | GLE1 |
Uniprot: | Q53GS7 |
Entrez: | 2733 |
Belongs to: |
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GLE1 family |
GLE1 (yeast homolog)-like, RNA export mediator; GLE1 RNA export mediator homolog (yeast); GLE1LGLE1 RNA export mediator-like (yeast); GLE1-like protein; GLE1-like, RNA export mediator; hGLE1GLE1 RNA export mediator (yeast); LCCS; LCCS1; lethal congenital contracture syndrome 1; nucleoporin GLE1
Mass (kDA):
79.836 kDA
Human | |
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Location: | 9q34.11 |
Sequence: | 9; NC_000009.12 (128504692..128542292) |
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm (PubMed:12668658). Shuttling is essential for its mRNA export function (PubMed:12668658).; [Isoform 1]: Cytoplasm. Nucleus, nuclear pore complex. Shuttles between the nucleus and the cytoplasm (PubMed:12668658). In the nucleus, isoform 1 localizes to the nuclear pore complex and nuclear envelope (PubMed:12668658). Shuttling is essential for its mRNA export function (PubMed:12668658).
PMID: 9618489 by Watkins J.L., et al. The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA export.
PMID: 12668658 by Kendirgi F., et al. An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export.