GJA1 Antibodies

AND GJA1 ELISA kits, GJA1 Proteins

Many biological assays use antibodies to detect GJA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GJA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GJA1 antibodies...

We validate the specificity of these antibodies to GJA1 by testing them on tissues known to express GJA1 positively and negatively. Browse below to find the GJA1 antibody that suites your experiment. We have 12 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GJA1 Infographic by Boster Bio

All GJA1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Connexin 43/GJA1 Antibody Picoband®

12 Citations 16 Q&As

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # PA1026
100 μg/vial

Anti-Connexin 43/GJA1 Antibody Picoband®

15 Citations 17 Q&As

Human, Mouse, Rat

IHC, ICC, WB

$370
Cat # PA1026-1
100 μg/vial

Anti-Phospho-Connexin43 (Ser368) GJA1 Antibody

4 Citations 3 Q&As

Mouse, Rat

$481
Cat # P00599
100 µl

Connexin 43 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1134
1 kit, containing one 96-well plate and all necessary reagents

Connexin 43 (Phospho-Ser367) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2378
1 kit, containing two 96-well plates and all necessary reagents

Anti-Connexin 43/GJA1 Antibody Picoband®

14 Citations 5 Q&As

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A00599
100 μg/vial

Anti-Connexin 43 (S369) GJA1 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A00599S369
100ul

Anti-Connexin 43 (phospho-S367) GJA1 Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A00599S367
100ul

Anti-Phospho-Connexin 43 (S368) GJA1 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A00599S368
100ul

Anti-Phospho-Connexin 43 (S265) GJA1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A00599S265
100ul

Anti-Phospho-Connexin 43 (S261) GJA1 Antibody

Human

ELISA, IHC

$380
Cat # A00599S261
100ul

GJA1 (NM_000165) Human Over-expression Lysate

Human

$628
Cat # LS002697
100 µg

GJA1 Overview

Facts about Gap junction alpha-1 protein.

GJA1 3D structure. Source: alphafold

Gap junction alpha-1 protein (GJA1)

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and making them contract (By similarity).

Gene Information

Human
Gene Name:	GJA1
Uniprot:	P17302
Entrez:	2697

Family

Belongs to:

connexin family

Alternative Names

Connexin 43; connexin-43; CX43; CX43gap junction protein, alpha-like; DFNB38; Gap junction 43 kDa heart protein; gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa (connexin 43); gap junction protein, alpha 1, 43kDa; GJA1; GJAL; HSS; ODD; ODDD; ODOD; SDTY3

Molecular Weight

Mass (kDA):
43.008 kDA

Genomic Context


Human

Location:	6q22.31
Sequence:	6; NC_000006.12 (121435646..121449727)

Tissue Specificity

Expressed in the heart and fetal cochlea.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65.

Diseases

Dysplasia
Oculo-dento-digital Syndrome
Eye Abnormalities
Syndactyly
Malignant Neoplasms
Tooth Abnormalities
Cardiac Arrhythmia
Neoplasms
Craniofacial Abnormalities
Tissue Adhesions
Limb Deformities, Congenital
Dental Enamel Hypoplasia
Heart Failure

Cardiac Fibrillation
Odontodysplasia
Hypoplasia
Atrial Fibrillation
Microphthalmos
Cardiomyopathies
Sensorineural Hearing Loss (disorder)

Interacting Proteins

TJP1

Pathways

Localization
Cell Proliferation
Spermatogenesis
Cell Adhesion
Parturition
Ovulation
Cell Differentiation
Fertilization
Cell Migration
Transport
Cell Development
Methylation
Secretion

Pathogenesis
Meiosis
Cell Growth
Cell Cycle
Oogenesis
Oocyte Maturation
Bone Remodeling

PTMs

Phosphorylation
Methylation
Acetylation
Demethylation
Nitrosylation

Reduction
Glycosylation
Cleavage
Oxidation
Dephosphorylation

Ubiquitination

Research Areas

Cancer
Core ESC-Like Genes
Neuronal Cell Markers
Neuroscience
Phospho-Specific

Signal Transduction
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GJA1

References

PMID: 1696265 by Fishman G.I., et al. Molecular characterization and functional expression of the human cardiac gap junction channel.

PMID: 1646158 by Fishman G.I., et al. The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures.

25 Publications of Boster GJA1 Antibodies & ELISA Kits

PubMed ID: 10.7150/thno.60160, Iron Oxide Nanoparticles Promote Cx43-Overexpression of Mesenchymal Stem Cells f...
PubMed ID: 10.3892/mmr.2012.1185, Recombinant human brain natriuretic peptide therapy combined with bone mesenchym...
PubMed ID: 10.3233/BME-141214, Expression of Cx43 and Pax3 proteins in the human placental villi and decidua du...
PubMed ID: 10.1186/1423-0127-19-6, Engineered myocardial tissues constructed in vivo using cardiomyocyte-like cells...
PubMed ID: 10.1159/000095501, Fibrosis of Collagen I and Remodeling of Connexin 43 in Atrial Myocardium of Pat...
PubMed ID: 10.1016/j.theriogenology.2021.09.008, LIF and bFGF enhanced chicken primordial follicle activation by Wnt/β-catenin p...
PubMed ID: 10.1016/j.reprotox.2012.12.002, Apocynin and raisanberine alleviate intermittent hypoxia induced abnormal StAR a...
PubMed ID: 10.1016/j.mce.2017.01.020, Mitochondrial Uncoupling Protein 2 in human cumulus cells is associated with reg...
PubMed ID: 10.1016/j.ejphar.2013.09.028, AQP4 KO exacerbating renal dysfunction is mediated by endoplasmic reticulum stre...
PubMed ID: 10.1016/j.bbrc.2016.10.115, Ectoderm mesenchymal stem cells promote differentiation and maturation of oligod...
PubMed ID: 10.1016/j.bbrc.2009.01.173, Chemical and physical stimuli induce cardiomyocyte differentiation from stem cel...
PubMed ID: 10.1016/j.acthis.2009.02.001, Differential expression of connexin 43 in human autoimmune thyroid disease
PubMed ID: , Perineurium-like sheath derived from long-term surviving mesenchymal stem cells ...
PubMed ID: 32343674, Liu Y,Bai H,Guo F,Thai PN,Luo X,Zhang P,Yang C,Feng X,Zhu D,Guo J,Liang P,Xu Z,Y...
PubMed ID: 31773683, Effect of celecoxib on protein expression of FAK and Cx43 in DMBA induced rat to...
PubMed ID: 27983986, Ectoderm mesenchymal stem cells promote differentiation and maturation of oligod...
PubMed ID: 27575818, Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins...
PubMed ID: 26450928, miR-381suppresses C/EBP?-dependent Cx43 expression in breast cancer cells
PubMed ID: 26283635, Identification of miR-200a as a novel suppressor of connexin 43in breast cancer ...
PubMed ID: 26775665, Argirein alleviates stress-induced and diabetic hypogonadism in rats via normali...
PubMed ID: 22426698, CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normaliz...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page