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GIMAP4 Antibodies
AND GIMAP4 ELISA kits, GIMAP4 Proteins
Many biological assays use antibodies to detect GIMAP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GIMAP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GIMAP4 antibodies...
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GIMAP4 Infographic by Boster Bio
All GIMAP4 Products
Product
Figures
Specificity
Applications
Price
Human
IF, IHC, WB
$523
Cat # M10738
100 µl
Cat # M10738
100 µl
Human
Flow Cytometry, IF, IHC, WB
$523
Cat # M10738-1
100 µl
Cat # M10738-1
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A10738-3
100 μg/vial
Cat # A10738-3
100 μg/vial
GIMAP4 Overview
Facts about GTPase IMAP family member 4.
GTPase IMAP family member 4 (GIMAP4)
May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity.
Shows a greater affinity for GDP over GTP (roughly 12-fold higher), and transmitting shows an absolute requirement for magnesium. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GIMAP4 |
| Uniprot: | Q9NUV9 |
| Entrez: | 55303 |
Family
| Belongs to: |
|---|
| TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily |
Alternative Names
GTPase IMAP family member 4; GTPase, IMAP family member 4; HIMAP4; human immune associated nucleotide 1; IAN-1; IAN1FLJ11110; IMAP4hIAN1; immunity associated protein 4; Immunity-associated nucleotide 1 protein; Immunity-associated protein 4
Molecular Weight
Mass (kDA):
37.534 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q36.1 |
| Sequence: | 7; NC_000007.14 (150567370..150573953) |
Tissue Specificity
Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Subcellular Localizations
Cytoplasm, cytosol.
Diseases
- Diabetes Mellitus
- Lymphopenia
- Diabetes Mellitus, Insulin-dependent
- Lymphomatoid Papulosis
- Adenocarcinoma
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Malignant Neoplasm Of Lung
- Malignant Neoplasms
- Leukemogenesis
- Malignant Squamous Cell Neoplasm
- Allergic Asthma
- Eczema
Pathways
- Cell Differentiation
- Programmed Cell Death
- Cell Death
- Neuroendocrine Cell Differentiation
- Immune Response
- T Cell Homeostasis
- Pathogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GIMAP4
bosterbio.com/bosterbio-gene-info-cards/GIMAP4
References
PMID: 11964296 by Cambot M., et al. Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells.
PMID: 16509771 by Nitta T., et al. IAN family critically regulates survival and development of T lymphocytes.