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- Table of Contents
Facts about Growth hormone variant.
It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Human | |
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Gene Name: | GH2 |
Uniprot: | P01242 |
Entrez: | 2689 |
Belongs to: |
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somatotropin/prolactin family |
GH2; GHL; GHV; GHVgrowth hormone variant; GH-VPlacenta-specific growth hormone; Growth Hormone 2; growth hormone 2hGH-V; placental-specific growth hormone
Mass (kDA):
25 kDA
Human | |
---|---|
Location: | 17q23.3 |
Sequence: | 17; NC_000017.11 (63880215..63881944, complement) |
Expressed in the placenta.
Secreted.
This article will describe Boster Bio's anti Growth Hormone (Pituitary marker) GH2 Monoclonal Antbody is and how it operates. I will also describe how to troubleshoot and test it. In the next section, I will also discuss some of the benefits that this product can provide. Keep reading! Thank you for reading!
Boster Bio's anti GH2 antibody reacts with human Growth Hormone. The antibody is accompanied by an inhibitory peptide with 1.0 mg/ml. All antibodies are validated by Boster Bio using WB and IHC methods. There are many suppliers who offer antibodies.
The product is tested using the gold standard method to ensure accuracy and reproducibility. The reagents are able to withstand diverse environments, including cell culture and bioreactors. Scientists can submit their findings for specific species and samples to earn product credits. All Boster scientists are eligible to earn product credits.
The monoclonal antibody anti-GH2 from Boster Bio is a potent immunotherapy that treats many pituitary diseases. It acts by binding to the human growth hormone receptors. It is highly sensitive. It can increase the binding to the human growth hormone that is radioiodinated by up to 40 percent. In addition the antibody's Scatchard analysis shows a higher number of binding sites than is seen in other monoclonal antibodies.
One in three to four thousand children is affected by a deficiency of growth hormone. Numerous chromosome abnormalities were identified. A rare case of GH deficiency and polymalformation syndrome is GH deficiency. A study of two brothers has confirmed that growth hormone deficiency results in the development of pre-auricular pits and an imperforate anus. MRI results have shown that the hypothalamic-pituitary axis is malformed in this rare condition.
The protein has seventy-one amino acids and is 43% identical to mammalian receptors. It is composed of ten exons. They are activated using a synthetic ligand. AMH-R II is expressed in COS-7 cells. Its resemblance to mammalian receptors suggests that the receptors are primitive and functionally overlapping.
The research conducted by Tannenbaum, G., and colleagues. in 1998 reported that boster Bio's Anti-Growth Hormone (Pituitary Marker) GH2 Monoclonal Antibody was effective in reducing pituitary growth hormone and other GH receptors.
The Anti-Growth Hormone (GH2) Monoclonal Antibody, RP1024, from Boster Bio reacts with Human GH2. The antibody is available in a 1.0 mg/ml dosage and stored at -20°C to 4°C for a period of one month. It is used in many reagents such as cell culture, tissue samples and cytopathic acids.
This product uses high-affinity primary antibodies, which are validated on Western Blotting and Immunohistochemistry. They can be used to determine both mouse and human genetic material. For larger samples multichannel pipettes are highly recommended. Boster's site has a wide collection of information about diseases. It contains blogs and technical resources as well as digital web-based tools. Boster products also utilize high-quality lysis buffers to guarantee excellent results. They also lower the intensity of cross-linking.
In most cases, returning your GH2 Marker to its factory default settings is the best method to solve the issue. These settings have been thoroughly examined for durability, durability and compatibility. If you find that your marker isn't performing according to your expectations, simply return it to its factory default settings and then test the settings that aren't factory defaults. The dwell time has no impact on ROF or velocity, and reduces the number markers cycles.
The first step is to check sure that your AA batteries and the rechargeable LiPo battery are fully charged and inserted correctly. Make sure that your power select switch remains in the ON position. If none of these steps are successful and your camera is not working, then you need an update to its software to correct the issue. If the issue persists, you should get in touch with the manufacturer to request the replacement. These steps will help you find solutions if still experiencing issues.
The GH2 biomarker is an important biomarker that can be used to detect various types of cancer. While it is crucial to remember that the GH hormone itself is not cancer-causing, it may help in the development of certain kinds of tumors. The tumors are detectable in human specimens using the GH2 marker. It is also used to diagnose hypothyroidism.
PMID: 7169009 by Seeburg P.H.; The human growth hormone gene family: nucleotide sequences show recent divergence and predict a new polypeptide hormone.
PMID: 3379057 by Cooke N.E., et al. Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins.