Non-lysosomal glucosylceramidase (GBA2)

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation.

May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such action is unclear in vivo. Plays a role in central nevous system development.