GAREM1 Antibodies

AND GAREM1 ELISA kits, GAREM1 Proteins

Many biological assays use antibodies to detect GAREM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GAREM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GAREM1 antibodies...

We validate the specificity of these antibodies to GAREM1 by testing them on tissues known to express GAREM1 positively and negatively. Browse below to find the GAREM1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GAREM1 Infographic by Boster Bio

All GAREM1 Products

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Anti-GAREM1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A12630-1
100 μg/vial

GAREM1 Overview

Facts about GRB2-associated and regulator of MAPK protein 1.

GAREM1 3D structure. Source: alphafold

GRB2-associated and regulator of MAPK protein 1 (GAREM1)

Isoform 1: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway.

Plays a role in the regulation of cell proliferation. .

Gene Information

Human
Gene Name:	GAREM1
Uniprot:	Q9H706
Entrez:	64762

Family

Belongs to:

GAREM family

Alternative Names

Chromosome 18 Open Reading Frame 11; chromosome 18 open reading frame 11, family with sequence; FAM59A; Family With Sequence Similarity 59, Member A; FLJ21610; GAREM; Gm944; GRB2 associated, regulator of MAPK1; Grb2-Associated And Regulator Of Erk/MAPK; GRB2-Associated And Regulator Of MAPK Protein; GRB2-Associated And Regulator Of MAPK1; Protein FAM59A

Molecular Weight

Mass (kDA):
97.186 kDA

Genomic Context


Human

Location:	18q12.1
Sequence:	18; NC_000018.10 (32263521..32470882, complement)

Tissue Specificity

Isoform 1 is ubiquitously expressed.

Diseases

Cell Transformation, Neoplastic
Malignant Neoplasms
Metaplastic Cell Transformation

Interacting Proteins

GRAP2
GRB2

Pathways

Endocytosis

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAREM1

References

PMID: 19509291 by Tashiro K., et al. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling.