Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2)

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b.

Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. .