GALNT3 Antibodies

AND GALNT3 ELISA kits, GALNT3 Proteins

Many biological assays use antibodies to detect GALNT3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GALNT3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GALNT3 antibodies...

We validate the specificity of these antibodies to GALNT3 by testing them on tissues known to express GALNT3 positively and negatively. Browse below to find the GALNT3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GALNT3 Infographic by Boster Bio

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Anti-GALNT3 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A04300
100ul

GALNT3 Overview

Facts about Polypeptide N-acetylgalactosaminyltransferase 3.

GALNT3 3D structure. Source: alphafold

Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3)

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5.

Likely glycosylates fibronectin in vivo. Glycosylates FGF23.

Gene Information

Human
Gene Name:	GALNT3
Uniprot:	Q14435
Entrez:	2591

Family

Belongs to:

glycosyltransferase 2 family

Alternative Names

EC 2.4.1.41; GalNAc transferase 3; GalNAc-T3; GalNAc-T3DKFZp686C10199; GALNT3; HFTC; HFTCMGC61909; HHS; HHSPolypeptide GalNAc transferase 3; polypeptide GalNAc-transferase T3; polypeptide N-acetylgalactosaminyltransferase 3; pp-GaNTase 3; Protein-UDP acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3; UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 3 (GalNAc-T3)

Molecular Weight

Mass (kDA):
72.61 kDA

Genomic Context


Human

Location:	2q24.3
Sequence:	2; NC_000002.12 (165747588..165796352, complement)

Tissue Specificity

Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney.

Subcellular Localizations

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Resides preferentially in the trans and medial parts of the Golgi stack.

Diseases

Calcinosis
Tumoral Calcinosis
Hyperphosphatemia
Neoplasms
Hyperostosis
Metabolic Diseases
Hyperostosis-hyperphosphatemia Syndrome
Hypophosphatemia
Malignant Neoplasms
Skin Neoplasms
Infertility
Hereditary Diseases
Osteomalacia

Rickets
Familial Hypophosphatemia
Familial Hypophosphatemic Bone Disease
Dermatologic Disorders
Hypophosphatemic Rickets
Phosphorus Metabolism Disorders
Ulcer

Interacting Proteins

APPBP2

Pathways

Secretion
Glycosylation
Pathogenesis
Renal Phosphate Excretion
Excretion
Sulfation
Transport
Proteolysis
Localization
Ion Homeostasis

Cell Differentiation
Amelogenesis
Rna Interference
Bone Mineralization

PTMs

Glycosylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GALNT3

References

PMID: 8663203 by Bennett E.P., et al. cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D- galactosamine polypeptide N-acetylgalactosaminyltransferase, GalNAc- T3.

PMID: 9295285 by Wandall H.H., et al. Substrate specificities of three members of the human UDP-N-acetyl- alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.