GABRD Antibodies

AND GABRD ELISA kits, GABRD Proteins

Many biological assays use antibodies to detect GABRD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GABRD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GABRD antibodies...

We validate the specificity of these antibodies to GABRD by testing them on tissues known to express GABRD positively and negatively. Browse below to find the GABRD antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GABRD Infographic by Boster Bio

All GABRD Products

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Product

Figures

Specificity

Applications

Price

Anti-GABRD/Gaba A Receptor Delta Antibody

1 Q&As

Human, Mouse, Rat

ELISA, IHC-P, WB, IF (paraffin)

$335
Cat # A30688
100ul

Anti-GABAA delta GABRD Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A06694
100ul

GABRD Overview

Facts about Gamma-aminobutyric acid receptor subunit delta.

GABRD 3D structure. Source: alphafold

Gamma-aminobutyric acid receptor subunit delta (GABRD)

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. .

Gene Information

Human
Gene Name:	GABRD
Uniprot:	O14764
Entrez:	2563

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

EIG10; EJM7; GABA A R delta; GABA(A) receptor subunit delta; GABA-A receptor, delta polypeptide; GABAAR delta; GABAARd; GABRD; gamma-aminobutyric acid (GABA) A receptor, delta; gamma-aminobutyric acid receptor subunit delta; GEFSP5; MGC45284

Molecular Weight

Mass (kDA):
50.708 kDA

Genomic Context


Human

Location:	1p36.33
Sequence:	1; NC_000001.11 (2019345..2030758)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Epilepsy
Epilepsy, Generalized
Febrile Convulsions
Epilepsies, Myoclonic
Depressive Disorder
1p36 Deletion Syndrome
Epilepsy, Temporal Lobe
Major Depressive Disorder
Epilepsies, Partial
Depression, Postpartum
Infantile Severe Myoclonic Epilepsy

Partial Seizure
Congenital Heart Defects
Myoclonic Epilepsy, Juvenile
Nervous System Disorder
Absence Epilepsy
Tonic-clonic Epilepsy

Interacting Proteins

NOTCH2NL
UBQLN1

Pathways

Pathogenesis
Feeding Behavior
Neuroprotection
Sensitization
Reverse Transcription
Response To Stress
Mrna Transcription
Parturition
Synaptic Transmission

Regulation Of Gene Expression
Cognition
Proestrus

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GABRD

References

PMID: 15115768 by Dibbens L.M., et al. GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies.

PMID: 27864847 by Parrini E., et al. Diagnostic targeted resequencing in 349 patients with drug-resistant pediatric epilepsies identifies causative mutations in 30 different genes.