GABRA2 Antibodies

AND GABRA2 ELISA kits, GABRA2 Proteins

Many biological assays use antibodies to detect GABRA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GABRA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GABRA2 antibodies...

We validate the specificity of these antibodies to GABRA2 by testing them on tissues known to express GABRA2 positively and negatively. Browse below to find the GABRA2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GABRA2 Infographic by Boster Bio

All GABRA2 Products

Product

Figures

Specificity

Applications

Price

Anti-GABRA2 Antibody (C-term)

Human

Flow Cytometry, IHC-P, WB

$298
Cat # A03996-1
80 µl

GABRA2 Overview

Facts about Gamma-aminobutyric acid receptor subunit alpha-2.

GABRA2 3D structure. Source: alphafold

Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2)

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. .

Gene Information

Human
Gene Name:	GABRA2
Uniprot:	P47869
Entrez:	2555

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

GABA A R alpha 2; GABA(A) receptor subunit alpha-2; GABAAR alpha 2; GABAARa2; GABRA2; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid receptor subunit alpha-2

Molecular Weight

Mass (kDA):
51.326 kDA

Genomic Context


Human

Location:	4p12
Sequence:	4; NC_000004.12 (46243548..46390300, complement)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Cell projection, dendrite.

Diseases

Anxiety Disorders
Dysequilibrium Syndrome
Mental Disorders
Schizophrenia
Epilepsy
Substance-related Disorders
Depressive Disorder
Nervousness
Diseases In Twins
Post-traumatic Stress Disorder

Cognition Disorders
Tobacco Use Disorder
Nicotine Dependence
Conduct Disorder
Stress, Psychological

Pathways

Reflex
Righting Reflex
Response To Alcohol
Brain Development
Cognition
Drinking Behavior
Sensitization
Response To Hypoxia
Synaptic Transmission
Localization
Response To Ethanol
Cell Death
Pathogenesis

Fear Response
Transport
Aging
Hypersensitivity
Neurogenesis
Drug Transport
Response To Cocaine

PTMs

Phosphorylation

Methylation

Research Areas

Neuronal Cell Markers
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GABRA2

References

PMID: 15024690 by Edenberg H.J., et al. Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.

PMID: 8391122 by Hadingham K.L., et al. Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma- aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.