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- Table of Contents
1 Citations 1 Q&As
Facts about Gamma-aminobutyric acid receptor subunit alpha-1.
Functions as receptor for diazepines and various anesthetics, such as pentobarbital; those are bound at a different allosteric effector binding site. Functions as ligand- gated chloride channel (By similarity).
Human | |
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Gene Name: | GABRA1 |
Uniprot: | P14867 |
Entrez: | 2554 |
Belongs to: |
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ligand-gated ion channel (TC 1.A.9) family |
ECA4; EJM; EJM5GABA(A) receptor subunit alpha-1; GABA A R alpha 1; GABAAR alpha 1; GABAARa1; GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid receptor subunit alpha-1
Mass (kDA):
51.802 kDA
Human | |
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Location: | 5q34 |
Sequence: | 5; NC_000005.10 (161847191..161899971) |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
PMID: 2465923 by Schofield P.R., et al. Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.
PMID: 2847710 by Garrett K.M., et al. Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor.
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