G2E3 Antibodies

AND G2E3 ELISA kits, G2E3 Proteins

Many biological assays use antibodies to detect G2E3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with G2E3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop G2E3 antibodies...

We validate the specificity of these antibodies to G2E3 by testing them on tissues known to express G2E3 positively and negatively. Browse below to find the G2E3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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G2E3 Infographic by Boster Bio

All G2E3 Products

Product

Figures

Specificity

Applications

Price

Anti-G2E3 Antibody

Human, Mouse, Rat

$405
Cat # A11602
100ul

G2E3 Overview

Facts about G2/M phase-specific E3 ubiquitin-protein ligase.

G2E3 3D structure. Source: alphafold

G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Critical in early embryonic development to prevent apoptotic death.

Gene Information

Human
Gene Name:	G2E3
Uniprot:	Q7L622
Entrez:	55632

Family

Belongs to:

No superfamily

Alternative Names

EC 6.3.2; EC 6.3.2.-; FLJ20333; G2/M phase-specific E3 ubiquitin-protein ligase; G2/M-phase specific E3 ubiquitin ligase; G2/M-phase specific E3 ubiquitin protein ligase; KIAA1333PHD finger protein 7B; PHF7B

Molecular Weight

Mass (kDA):
80.504 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (30559123..30620064)

Tissue Specificity

Predominantly expressed in brain, liver, kidney, testes and ovary.

Subcellular Localizations

Nucleus, nucleolus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage.

Diseases

Nervousness

Interacting Proteins

RPS15

Pathways

Cell Cycle
Cell Division
Stem Cell Division
Cell Death
Limb Bud Formation
Localization

Nuclear Export

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/G2E3

References

PMID: 17239372 by Brooks W.S., et al. G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization.

PMID: 11483598 by Crawford D.F., et al. The G(2) DNA damage checkpoint delays expression of genes encoding mitotic regulators.