FXYD3 Antibodies

AND FXYD3 ELISA kits, FXYD3 Proteins

Many biological assays use antibodies to detect FXYD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FXYD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FXYD3 antibodies...

We validate the specificity of these antibodies to FXYD3 by testing them on tissues known to express FXYD3 positively and negatively. Browse below to find the FXYD3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FXYD3 Infographic by Boster Bio

All FXYD3 Products

Product

Figures

Specificity

Applications

Price

FXYD3 (NM_005971) Human Recombinant Protein

$1249
Cat # PROTQ14802
20 µg

Anti-FXYD3 Mouse Monoclonal Antibody [Clone ID: OTI1D1]

Human

Flow Cytometry, IF, WB

$523
Cat # M08697-1
100 µl

Anti-FXYD3 Mouse Monoclonal Antibody [Clone ID: OTI1E8]

+10

Human

IF, IHC, WB

$523
Cat # M08697
100 µl

FXYD3 (NM_005971) Human Over-expression Lysate

Human

$628
Cat # LS005349
100 µg

FXYD3 Overview

Facts about FXYD domain-containing ion transport regulator 3.

FXYD3 3D structure. Source: alphafold

FXYD domain-containing ion transport regulator 3 (FXYD3)

Associates with and modulates the activity of this sodium/potassium-transporting ATPase (NKA) which transports Na(+) from the cell and K(+) into the cell (PubMed:17077088). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (PubMed:21454534).

Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (PubMed:7836447). .

Gene Information

Human
Gene Name:	FXYD3
Uniprot:	Q14802
Entrez:	5349

Family

Belongs to:

FXYD family

Alternative Names

Chloride conductance inducer protein Mat-8; FXYD domain containing ion transport regulator 3; FXYD domain-containing ion transport regulator 3; Mammary tumor 8 kDa protein; MAT8MAT-8; phospholemman-like protein; Phospholemman-like; PLMLMGC111076

Molecular Weight

Mass (kDA):
9.263 kDA

Genomic Context


Human

Location:	19q13.12
Sequence:	19; NC_000019.10 (35115818..35124324)

Tissue Specificity

Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level).

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Mammary Neoplasms
Carcinoma
Adenocarcinoma
Carcinoma, Transitional Cell
Malignant Neoplasm Of Pancreas
Lymphatic Metastasis
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Urinary Bladder
Bladder Neoplasm
Metastatic Malignant Neoplasm To The Lymph Node

Neoplasm Invasiveness
Transitional Cell Carcinoma Of Bladder
Colorectal Neoplasms
Malignant Neoplasm Of Kidney
Tumor Progression
Colorectal Cancer
Mucinous Adenocarcinoma

Interacting Proteins

EBP
MGST1
SLC39A2

Pathways

Transport
Cell Proliferation
Ion Transport
Localization
Cell Death
Cellular Localization
Developmental Process
Programmed Cell Death
Cellular Homeostasis
Glycosylation
Dna Repair
Muscle Contraction

Virulence
Methylation
Reverse Transcription
Cell Differentiation
Dedifferentiation
Cell Growth

PTMs

Phosphorylation
Cleavage

Glutathionylation
Glycosylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FXYD3

References

PMID: 7836447 by Morrison B.W., et al. Mat-8, a novel phospholemman-like protein expressed in human breast tumors, induces a chloride conductance in Xenopus oocytes.

PMID: 17077088 by Bibert S., et al. Structural and functional properties of two human FXYD3 (Mat-8) isoforms.