This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Four and a half LIM domains protein 1.
Human | |
---|---|
Gene Name: | FHL1 |
Uniprot: | Q13642 |
Entrez: | 2273 |
Belongs to: |
---|
No superfamily |
bA535K18.1; FHL1; four and a half LIM domains 1; HLH1; HPLH1; KYOT; KYO-T; LIM protein SLIMMER; skeletal muscle LIM-protein1; SLIM1; SLIM1Isl-1 and Mec-3 domains 1; SLIMMER; XMPMA
Mass (kDA):
36.263 kDA
Human | |
---|---|
Location: | Xq26.3 |
Sequence: | X; NC_000023.11 (136146702..136211359) |
Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle.
[Isoform 1]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.; [Isoform 2]: Nucleus. Cytoplasm, cytosol. Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes.
PMID: 8753811 by Morgan M.J., et al. Slim defines a novel family of LIM-proteins expressed in skeletal muscle.
PMID: 9714789 by Lee S.M.Y., et al. Chromosomal mapping, tissue distribution and cDNA sequence of four- and-a-half LIM domain protein 1 (FHL1).