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Proto-oncogene FRAT1 Antibodies

AND FRAT1 ELISA kits, Proto-oncogene FRAT1 Proteins

Many biological assays use antibodies to detect Proto-oncogene FRAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proto-oncogene FRAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proto-oncogene FRAT1 antibodies...

We validate the specificity of these antibodies to Proto-oncogene FRAT1 by testing them on tissues known to express FRAT1 positively and negatively. Browse below to find the FRAT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FRAT1 Infographic by Boster Bio

FRAT1 protein infographic

All FRAT1 Products

Product

Figures

Specificity

Applications

Price

Anti-Proto-oncogene FRAT1 FRAT1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08049
100ul

Anti-FRAT1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M08049
100 μl/vial

FRAT1 (NM_005479) Human Over-expression Lysate

Human

$628
Cat # LS010023
100 µg

FRAT1 Overview

Facts about Proto-oncogene FRAT1.

FRAT1 3D structure

FRAT1 3D structure. Source: alphafold

Proto-oncogene FRAT1 (FRAT1)

Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the institution with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.

.

Gene Information

Human
Gene Name:	FRAT1
Uniprot:	Q92837
Entrez:	10023

Gene Information

Family

Belongs to:

GSK-3-binding protein family

Family

Alternative Names

FLJ97193; FRAT-1; Frequently rearranged in advanced T-cell lymphomas 1; frequently rearranged in advanced T-cell lymphomas; proto-oncogene FRAT1

Molecular Weight

Mass (kDA):
29.093 kDA

Molecular Weight

Genomic Context


Human

Location:	10q24.1
Sequence:	10; NC_000010.11 (97319271..97321915)

Subcellular Localizations

Cytoplasm.

Subcellular Localization

Diseases

Neoplasms
Malignant Neoplasms
Lymphoma
T-cell Lymphoma
Leukemia
Carcinogenesis
Tumor Progression
Cell Transformation, Neoplastic
Malignant Neoplasm Of Stomach
Neoplasm Metastasis
Malignant Tumor Of Cervix
Carcinoma
Malignant Paraganglionic Neoplasm

Leukemogenesis
Metastatic Malignant Neoplasm To The Lymph Node
Embryonal Carcinoma
Malignant Neoplasm Of Breast
Neoplasms, Experimental
Myeloid Leukemia, Chronic
Myeloid Leukemia

Disease

Interacting Proteins

GSK3A
GSK3B

Interacting Proteins

Pathways

Localization
Nuclear Export
Cell Death
Nuclear Import
Endoderm Formation
Hair Follicle Morphogenesis
Cell Proliferation
Gene Silencing
Proteolysis
Dna Methylation
Methylation
Neuroprotection
Regeneration

Tissue Regeneration
Cell Cycle
Cell Motility
Establishment Of Tissue Polarity
Cell Growth
Peptide Secretion
Pathogenesis

Pathways

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Wnt Signaling Pathway

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRAT1

References

PMID: 9034327 by Jonkers J., et al. Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.

PMID: 11894125 by Saitoh T., et al. Molecular cloning and expression of proto-oncogene FRAT1 in human cancer.