CHAF1A Antibodies

AND CHAF1A ELISA kits, CHAF1A Proteins

Many biological assays use antibodies to detect CHAF1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHAF1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHAF1A antibodies...

We validate the specificity of these antibodies to CHAF1A by testing them on tissues known to express CHAF1A positively and negatively. Browse below to find the CHAF1A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHAF1A Infographic by Boster Bio

All CHAF1A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CAF-1 p150 CHAF1A Antibody

5 Q&As

Human, Mouse

$399
Cat # A02732-1
100μl

Anti-p150 CAF1 CHAF1A Antibody

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A02732
100ul

Anti-p150 CAF1 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02732-1
100 μl/vial

CAF1 (CHAF1A) (NM_005483) Human Over-expression Lysate

Human

$628
Cat # LS010036
100 µg

CHAF1A Overview

Facts about Chromatin assembly factor 1 subunit A.

CHAF1A 3D structure. Source: alphafold

Chromatin assembly factor 1 subunit A (CHAF1A)

Core part of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro.

CAF-1 performs the initial step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor following DNA replication to finish the histone octamer. CHAF1A binds to histones H3 and H4.

Gene Information

Human
Gene Name:	CHAF1A
Uniprot:	Q13111
Entrez:	10036

Family

Belongs to:

CHAF1A family

Alternative Names

CAF; CAF-1 subunit A; CAF1; CAF-1; CAF1B; CAF1P150CAF-I 150 kDa subunit; CAF-I p150; chromatin assembly factor 1 subunit A; chromatin assembly factor 1, subunit A (p150); chromatin assembly factor I (150 kDa); Chromatin assembly factor I p150 subunit; hp150; MGC71229; P150

Molecular Weight

Mass (kDA):
106.91 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (4402596..4448322)

Subcellular Localizations

Nucleus. DNA replication foci.

Diseases

Cytomegalovirus Infections
Exposure To Ionizing Radiation
Neoplasms
Glioma
Mammary Neoplasms
Malignant Paraganglionic Neoplasm
Brain Neoplasms

Carcinogenesis

Interacting Proteins

CBX5
GFI1
H3F3A
HIST2H3A
MBD1

NCK1
PCNA
PIK3R1
REL
TCF4

Pathways

Chromatin Assembly
Dna Replication
Nucleosome Assembly
Cell Cycle
S Phase
Gene Silencing
Mitosis
Localization
Dna Repair
Cell Proliferation
Dna Methylation
Methylation
Cell Division

G2 Phase
Chromosome Segregation
Demethylation
Mismatch Repair
Response To Uv
Cell Death
Interphase

PTMs

Phosphorylation
Acetylation
Methylation

Reduction
Dephosphorylation
Ubiquitination

Research Areas

Apoptosis
Cancer
Cell Cycle and Replication
Chromatin Research
Core ESC-Like Genes

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHAF1A

References

PMID: 11250073 by Dong H., et al. Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene.

PMID: 7600578 by Kaufman P.D., et al. The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication.