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- Table of Contents
Facts about Forkhead box protein P2.
Can act with CTBP1 to repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels.
Human | |
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Gene Name: | FOXP2 |
Uniprot: | O15409 |
Entrez: | 93986 |
Belongs to: |
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No superfamily |
CAG repeat protein 44; CAGH44; CAGH44TNRC10forkhead box protein P2; DKFZp686H1726; forkhead box P2; forkhead/winged-helix transcription factor; FoxP2; SPCH1; TNRC10; trinucleotide repeat containing 10; Trinucleotide repeat-containing gene 10 protein
Mass (kDA):
79.919 kDA
Human | |
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Location: | 7q31.1 |
Sequence: | 7; NC_000007.14 (114086327..114693772) |
Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung.
Nucleus.
PMID: 11586359 by Lai C.S.L., et al. A forkhead-domain gene is mutated in a severe speech and language disorder.
PMID: 12189486 by Bruce H.A., et al. FOXP2: novel exons, splice variants, and CAG repeat length stability.