Forkhead box protein O3 Antibodies

AND FOXO3 ELISA kits, Forkhead box protein O3 Proteins

Many biological assays use antibodies to detect Forkhead box protein O3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Forkhead box protein O3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Forkhead box protein O3 antibodies...

We validate the specificity of these antibodies to Forkhead box protein O3 by testing them on tissues known to express FOXO3 positively and negatively. Browse below to find the FOXO3 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FOXO3 Infographic by Boster Bio

All FOXO3 Products

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Product

Figures

Specificity

Applications

Price

Anti-FOXO3A Antibody Picoband®

1 Citations 5 Q&As

Human, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9196
100 μg/vial

Anti-Phospho-FoxO3a (S253) Rabbit Monoclonal Antibody

15 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # P00252
100 μl

Anti-FoxO3a Rabbit Monoclonal Antibody

16 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # M00252-1
100 μl

Anti-FoxO3a Rabbit Monoclonal Antibody

15 Q&As

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M00252
100 μl

Anti-Forkhead box protein O3 FOXO3 Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$449
Cat # A00252
0.1 mg

Anti-FoxO3A (phospho-S253) Antibody

Human, Mouse

IF, IHC, WB

$482
Cat # A00252S253
100ul

Anti-FoxO3A (phospho-S253) Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A00252S253-1
100ul

FOXO3 (NM_001455) Human Over-expression Lysate

Human

$628
Cat # LS002309
100 µg

Anti-FOXO3A/FOXO3 Antibody Picoband®

Human

ELISA, WB

$370
Cat # A00252-2
100 µg/vial

FOXO3 Overview

Facts about Forkhead box protein O3.

FOXO3 3D structure. Source: alphafold

Forkhead box protein O3 (FOXO3)

Transcriptional activator which activates apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882).

Participates in post-transcriptional regulation of MYC: after phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, two post-transcriptional labs of MYC that bind to the 3'UTR of MYC transcript and prevent its interpretation (PubMed:21329882). In response to metabolic stress, translocates to the mitochondria where it promotes mtDNA transcription (PubMed:23283301).

Gene Information

Human
Gene Name:	FOXO3
Uniprot:	O43524
Entrez:	2309

Family

Belongs to:

No superfamily

Alternative Names

AF6q21 protein; AF6q21; DKFZp781A0677; FKHRL1; FKHRL1MGC31925; FKHRL1P2; forkhead box O3; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; Forkhead in rhabdomyosarcoma-like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO2; FoxO3; FOXO3A; FOXO3Aforkhead box O3A; MGC12739

Molecular Weight

Mass (kDA):
71.277 kDA

Genomic Context


Human

Location:	6q21
Sequence:	6; NC_000006.12 (108559825..108684774)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. Mitochondrion matrix. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Retention in the cytoplasm contributes to its inactivation (PubMed:10102273, PubMed:15084260, PubMed:16751106). Translocates to the nucleus upon oxidative stress and in the absence of survival factors (PubMed:10102273, PubMed:16751106). Translocates from the cytosol to the nucleus following dephosphorylation in response to autophagy-inducing stimuli (By similarity). Translocates in a AMPK-dependent manner into the mitochondrion in response to metabolic stress (PubMed: